Instruments
Transmission Electron Microscopy (TEM)
The JEOL 1400 Transmission Electron Microscope is a high-contrast, high-resolution instrument utilizing a LaB6 filament, and capable of operating at accelerating voltages up to 120 kV. Contact Nicole Bishop, Michele von Turkovich, or Janet Schwarz for information about use.
Scanning Electron Microscopy (SEM)
The JEOL 6060 scanning electron microscope is used for investigations of bulk specimens. Contact Michele von Turkovich for information about use.
Confocal Laser Microscopy
A key feature of confocal microscopy is, through rastered laser scanning, the ability to build up point by point a well defined digital image, virtually eliminating out of focus fluorescence, which results in increased detection, contrast and resolution. Contact Nicole Bishop, or Nicole Bouffard for information about use.
Atomic Force Microscope (AFM)
The Asylum Research MFP-3D BIO AFM allows investigation of biological/materials surfaces at high resolution. Contact Nicole Bouffard for information about use.
Light Microscopy
Olympus BX50 Light Microscope with QImaging Retiga 2000R digital camera with double and triple fluorescence staining capabilities and software for image management and archiving.Contact Nicole Bishop, or Nicole Bouffard for information about use.
ECIS Electric Cell Substrate Impedance Sensing
An ECIS system (from Applied BioPhysics, Inc. Troy, NY) measures impedance, resistance, and capacitance in cultured cells grown on specially-fabricated chamber slides fitted with gold film-coated microelectrode. Contact Douglas Taatjes for information about use.
Laser Scanning Cytometry
The Compucyte Laser Scanning Cytometer provides data similar to that obtained from a flow cytometer, but has the advantage of being microscope-slide based. Contact Janet Schwarz for information about use.
Laser Capture Microdissector
The Arcturus (Life Technologies) XT-Ti Laser Capture Microdissector system is used for specifically removing desired cells from a tissue section for subsequent molecular analysis. Contact Janet Schwarz for information about use.
Super Resolution Microscope
Nikon N-STORM super-resolution microscope system consisting of a Nikon Ti-E TIRF inverted microscope base with laser modules. Contact Nicole Bishop, or Nicole Bouffard for information about use.
Image Analysis Software
Microscopy Center software includes: Universal Imaging MetaMorph Workstation, PerkinElmer Volocity 3D Rendering Software and MBF StereoInvestigator Software. Contact Nicole Bishop, or Nicole Bouffard for information about use.
IVIS Whole Animal Imager
Caliper LifeSciences IVIS Lumina II Whole Animal In Vivo Imaging System is used to image quantitative fluorescent and bioluminescent probes in live mice. Contact Nicole Bishop, or Nicole Bouffard for information about use.