Leica-Aperio VERSA 8 whole slide scanner

Leica Whole Slide ScannerThe highly versatile Leica-Aperio VERSA 8 is an automated scanning microscope and image generation scanning system. Some of its features include: integrated brightfield and fluorescence scanner; two high quality CMOS cameras for brightfield or fluorescence image acquisition; batch set-up and automation for unsupervised scanning of up to 8 slides; fluorescent scanning of up to 7 fluorophores/slide; and a wide range of Leica quality objective lenses (1.25, 5, 10, 20, 40, and 63X). Software allows low magnification overview of an entire sample, with high resolution “zoom in” feature to analyze cellular features.



CD34 staining on TMA

Recent papers published from the MIC:

  • Cunniff, B., et al. (2015). "Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma." PLoS One 10(5): e0127310.
  • F. E., et al. (2017). "Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis." Methods Mol Biol 1627: 253-283.
  • Kumar, A., et al. (2022). "Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis." Thorax 77(7): 669-678.
  • Nakada, E. M., et al. (2019). "Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers." JCI Insight 4(9).
  • Taatjes, D. J., et al. (2019). "Quantitative pixel intensity- and color-based image analysis on minimally compressed files: implications for whole-slide imaging." Histochem Cell Biol 152(1): 13-23.
  • Tykocki, N. R., et al. (2018). "Development of stress-induced bladder insufficiency requires functional TRPV1 channels." Am J Physiol Renal Physiol 315(6): F1583-F1591.
  • van de Wetering, C., et al. (2020). "Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease." J Immunol.Uhl,

Additional publications located here.