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2022 Rising Star Visiting Professor: Kellie Machlus, PhD

April 30, 2023 by Cardiovascular Research Institute of Vermont

Kellie Machlus, PhD received her B.S. in biochemistry from the University of Delaware. She then obtained her Ph.D. in Pathology at the University of North Carolina at Chapel Hill under the mentorship of Alisa Wolberg, studying the association between hypercoagulability and thrombosis. Dr. Machlus then completed her postdoctoral fellowship at Brigham and Women’s Hospital and Harvard Medical School with Joseph Italiano, where she examined mechanisms that modulate and trigger proplatelet formation from megakaryocytes. She now runs an independent lab at Harvard Medical School where she focuses on mediators of megakaryocyte differentiation, maturation, and platelet production, with a strong focus on how these things are modulated during inflammation.

Kellie Machlus, PhD is an early career scientist at the Boston Children’s Hospital who is interested in studying megakaryocyte differentiation and maturation with a focus on how they are mediated by inflammation. Other and newer avenues of research she is looking at include: extracellular vesicles, how lipids affect megakaryocyte production, hematopoiesis and obesity.

Her events included a Scholar's Tea for early career junior investigators, fellows and trainees, an interactive Career Development seminar titled "Cultivating Leadership in  Yourself and Others Through Trust and Kindness" and a Medicine Grand Rounds program titled "Novel Mechanisms Regulating Megakaryocyte Differentiation and Platelet Production".  *These events were made possible by a generous gift from many donors to the Jim Ray Memorial Heart Ride.

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