Publications

McCabe, MP, Shore, AN, Frankel, WN, & Weston, MC (2021). Altered fast synaptic transmission in a mouse model of DNM1-associated developmental epileptic encephalopathy. eNeuro, 8(2), ENEURO.0269-20.2020. 

Weston MC (2021). A tRNA variant translates into seizure resistance. Epilepsy Currents, 21(2), 126–128. 

Weston MC (2020). The heated relationship between neural activity and seizures. Epilepsy Currents, 21(1), 62–63. 

Shore, AN, Colombo, S, Tobin, WF, Petri, S, Cullen, ER, Dominguez, S, Bostick, CD, Beaumont, MA, Williams, D, Khodagholy, D, Yang, M, Lutz, CM, Peng, Y, Gelinas, JN, Goldstein, DB, Boland, MJ, Frankel, WN, & Weston, MC (2020). Reduced GABAergic neuron excitability, altered synaptic connectivity, and seizures in a KCNT1 gain-of-function mouse model of childhood epilepsy. Cell Reports, 33(4), 108303. 

McCabe, MP, Cullen, ER, Barrows, CM, Shore, AN, Tooke, KI, Laprade, KA, Stafford, JM, & Weston, MC (2020). Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission. eLife, 9, e51440. 

Sah, M, Shore, AN, Petri, S, Kanber, A, Yang, M, Weston, MC, & Frankel, WN (2020). Altered excitatory transmission onto hippocampal interneurons in the IQSEC2 mouse model of X-linked neurodevelopmental disease. Neurobiology of Disease, 137, 104758. 

Weston MC (2020). Vulnerabilities in a dominant receptor subunit. Epilepsy Currents, 20(2), 97–98. 

Weston MC (2020). KCC2 much chloride might not be the only problem. Epilepsy Currents, 20(1), 43–44. 

Weston MC (2018). Jumping to conclusions about focal seizure spread. Epilepsy Currents, 18(6), 394–395. 

Weston MC (2018). Trading up to a new model of STXBP-encephalopathy. Epilepsy Currents, 18(4), 257–259. 

Tobin, WF & Weston, MC (2018). Focusing on the big picture: Induced focal seizures propagate along synaptic pathways. Epilepsy Currents, 18(1), 47–48. 

Weston MC (2017). GRIN and bear the diverse functional effects of rare NMDA receptor variants. Epilepsy Currents, 17(6), 381–383. 

Barrows, CM, McCabe, MP, Chen, H, Swann, JW, & Weston, MC (2017). PTEN loss increases the connectivity of fast synaptic motifs and functional connectivity in a developing hippocampal network. Journal of Neuroscience, 37(36), 8595–8611. 

Weston MC (2017). The role of PRRT2 in synaptic transmission may not be so benign. Epilepsy Currents, 17(3), 165–166. 

John Lin, CC, Yu, K, Hatcher, A, Huang, TW, Lee, HK, Carlson, J, Weston, MC, Chen, F, Zhang, Y, Zhu, W, Mohila, CA, Ahmed, N, Patel, AJ, Arenkiel, BR, Noebels, JL, Creighton, CJ, & Deneen, B (2017). Identification of diverse astrocyte populations and their malignant analogs. Nature Neuroscience, 20(3), 396–405.

McCabe, MP & Weston, MC (2016). Riding the calcium wave to a better understanding of ictal events. Epilepsy Currents, 16(5), 333–334. 

Weston, MC, Chen, H, & Swann, JW (2014). Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures. Frontiers in Molecular Neuroscience, 7, 1. 

Weston, MC, Chen, H, & Swann, JW (2012). Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission. Journal of Neuroscience, 32(33), 11441–11452. 

Weston, MC, Nehring, RB, Wojcik, SM, & Rosenmund, C (2011). Interplay between VGLUT isoforms and endophilin A1 regulates neurotransmitter release and short-term plasticity. Neuron, 69(6), 1147–1159. 

Chaudhry, C, Weston, MC, Schuck, P, Rosenmund, C, & Mayer, ML (2009). Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. EMBO Journal, 28(10), 1518–1530. 

Martens, H, Weston, MC, Boulland, JL, Grønborg, M, Grosche, J, Kacza, J, Hoffmann, A, Matteoli, M, Takamori, S, Harkany, T, Chaudhry, FA, Rosenmund, C, Erck, C, Jahn, R, & Härtig, W (2008). Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses. Journal of Neuroscience, 28(49), 13125–13131. 

Albright, MJ, Weston, MC, Inan, M, Rosenmund, C, & Crair, MC (2007). Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice. Journal of Neurophysiology, 98(3), 1610–1625. 

Weston, MC, Schuck, P, Ghosal, A, Rosenmund, C, & Mayer, ML (2006). Conformational restriction blocks glutamate receptor desensitization. Nature Structural & Molecular Biology, 13(12), 1120–1127. 

Moechars, D, Weston, MC, Leo, S, Callaerts-Vegh, Z, Goris, I, Daneels, G, Buist, A, Cik, M, van der Spek, P, Kass, S, Meert, T, D'Hooge, R, Rosenmund, C, & Hampson, RM (2006). Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. Journal of Neuroscience, 26(46), 12055–12066. 

Weston, MC, Gertler, C, Mayer, ML, & Rosenmund, C (2006). Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate. Journal of Neuroscience, 26(29), 7650–7658. 

Stornetta, RL, Rosin, DL, Simmons, JR, McQuiston, TJ, Vujovic, N, Weston, MC, & Guyenet, PG (2005). Coexpression of vesicular glutamate transporter-3 and gamma-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column. Journal of Comparative Neurology, 492(4), 477–494. 

Mulkey, DK, Stornetta, RL, Weston, MC, Simmons, JR, Parker, A, Bayliss, DA, & Guyenet, PG (2004). Respiratory control by ventral surface chemoreceptor neurons in rats. Nature Neuroscience, 7(12), 1360–1369. 

Guyenet, PG, Stornetta, RL, Weston, MC, McQuiston, T, & Simmons, JR (2004). Detection of amino acid and peptide transmitters in physiologically identified brainstem cardiorespiratory neurons. Autonomic Neuroscience : Basic & Clinical, 114(1-2), 1–10. 

Weston, MC, Stornetta, RL, & Guyenet, PG (2004). Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats. Journal of Comparative Neurology, 473(1), 73–85. 

Wang, H, Weston, MC, McQuiston, TJ, Stornetta, RL, & Guyenet, PG (2003). Neurokinin-1 receptor-expressing cells regulate depressor region of rat ventrolateral medulla. American Journal of Physiology-Heart and Circulatory Physiology, 285(6), H2757–H2769. 

Rosin, DL, Weston, MC, Sevigny, CP, Stornetta, RL, & Guyenet, PG (2003). Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2. Journal of Comparative Neurology, 465(4), 593–603. 

Guyenet, PG, Sevigny, CP, Weston, MC, & Stornetta, RL (2002). Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic. Journal of Neuroscience, 22(9), 3806–3816.