Research Faculty

PrachiGhule2010Prachi Ghule, Ph.D., Assistant Professor

Cell cycle control of histone genes in human embryonic stem and induced pluripotent stem (iPS) cells. Subnuclear organization of cell cycle regulatory factors in Histone Locus Bodies. Molecular mechanisms of cell cycle control during early embryogenesis using HINFP knock-out mice. Multispectral and spatial transcriptomic analysis of breast cancer-compromised gene expression and crosstalk between breast tumors and the tumor microenvironment. 



JonathanGordonJonathan Gordon, Ph.D., Assistant Professor

Genomics of homeobox proteins, Runx2 and chromatin remodeling factors during osteogenesis. Profiling of lineage- selected cells during osteogenic differentiation using GFP mouse models. Bone-related regulatory networks and epigenetic mechanisms by high-throughput sequencing (DeepSeq). Multiomic and single-cell analysis of gene expression in breast cancer and osteosarcoma. 



Long noncoding RNAs (lncRNAs) in osteogenic differentiation of mesenchymal stromal cells. lncRNA regulation of cancer phenotype, with particular interest to lncRNAs involved in bone metastasis. Whole transcriptome sequencing (RNA-Seq).