LCOM & Department News

VCCBH Symposium Highlights Early Career Investigators, Innovative Multidisciplinary Research

June 29, 2022 by Jennifer Nachbur and Masayo Koide, Ph.D.

More than 100 in-person and dozens of virtual participants attended the second annual Vermont Center for Cardiovascular and Brain Health (VCCBH) Symposium, held at the University of Vermont’s Davis Center June 2 to 3, 2022. The VCCBH, one of three National Institutes of Health Center of Biomedical Research Excellence-funded programs at UVM, is co-directed by Mary Cushman, M.D., M.Sc., professor and vice chair for emerging researchers in the Department of Medicine, and Mark Nelson, Ph.D., University Distinguished Professor and chair of the Department of Pharmacology.

(Clockwise, from top left): Debora Kamin-Mukaz, Ph.D.; Thomas Heppner, Ph.D., and Gerald Herrerra, Ph.D.; Maddie Hatch, Dr. Cushman, and Rusul Mustafa.

More than 100 in-person and dozens of virtual participants attended the second annual Vermont Center for Cardiovascular and Brain Health (VCCBH) Symposium, held at the University of Vermont’s Davis Center June 2 to 3, 2022. The VCCBH, one of three National Institutes of Health Center of Biomedical Research Excellence (COBRE)-funded programs at UVM, is co-directed by Mary Cushman, M.D., M.Sc., professor and vice chair for emerging researchers in the Department of Medicine, and Mark Nelson, Ph.D., University Distinguished Professor and chair of the Department of Pharmacology.

Established in 2020, the VCCBH aims to improve the understanding of – and optimize treatments for – cardiovascular and neurovascular diseases through research conducted by a multidisciplinary team of clinicians, physician-scientists, basic scientists, statisticians, and other researchers. With the first symposium held virtually in 2021, this was the first time this group of collaborators was able to gather in person since the launch of the VCCBH in 2020. Attendees included UVM faculty and staff, as well as researchers from across the U.S., and world.

During the welcoming ceremonies at the start of the symposium, UVM Larner College of Medicine Dean Richard L. Page, M.D., presented an in-person welcome, and congratulatory remarks from Vermont Senator Patrick Leahy were read to attendees.

Highlights of the two-day event included a “Science Keynote Address,” delivered by Joseph Loscalzo, M.D., chair of medicine and Hersey Professor of the Theory and Practice of Medicine at Brigham & Women’s Hospital and Harvard Medical School. Titled “What is Disease? Defining Pathobiology and Therapeutics in the Era of Big Data,” his presentation focused on the process of developing new therapeutics using databases of protein-protein and structural interactions. The “Diversity and Inclusion Keynote Address” was presented by Michelle Albert, M.D., president-elect of the American Heart Association and professor of medicine and director of the CeNter for the StUdy of AdveRsiTy and CardiovascUlaR DiseasE (NURTURE Center) at the University of California at San Francisco. Titled “Breaking the Shackles: Addressing the Taxonomy of Medical Training to Achieve Health Equity,” her talk discussed the role of structural racism in health inequities, the need for BIPOC individuals to go into medicine, and methods that medical training programs can use to reduce the barriers to success for these individuals.

“Over two days, novel findings – ranging from the molecular level to human epidemiological analysis – brought lively discussions and raised future possible collaborations in the VCCBH research community,” said Masayo Koide, Ph.D., assistant professor of pharmacology and one of the four project directors for the VCCBH.

Additional presentations during the two-day symposium included research talks by VCCBH project directors, pilot grant awardees, and other faculty members. There was an exciting Flash Talk session including rapid fire presentations by seven VCCBH Pipeline Investigators. “Connection Corner” allowed attendees to speak with experts on career development topics.

A panel of five volunteers judged the poster session, including Nels Olson, Ph.D., assistant professor of pathology and laboratory medicine, Neil Zakai, M.D., M.Sc., professor of medicine, Peter Durda, Ph.D., faculty scientist in pathology and laboratory medicine, Maria Bravo, Ph.D., faculty scientist in biochemistry, and Amreen Mughal, Ph.D., assistant professor of pharmacology. Awardees included Maddie Hatch, a doctoral student in chemistry, Swapna Balakrishnan, PT, D.P.T, an interprofessional health sciences doctoral student, Margaret Phillips, Ph.D., a postdoctoral associate in pharmacology, Matthew Caporizzo, Ph.D., assistant professor in molecular physiology and biophysics, and Katharine Cheung, M.D., Ph.D., assistant professor of medicine.

“It is really reflective of our multidisciplinary community that the winners came from three UVM colleges,” said Cushman.

The third annual VCCBH symposium is scheduled for June 2023.

Link to the 2022 VCCBH Symposium agenda

 

Past Department Highlights

Congratulations to the following individuals on their promotions effective July 1, 2024. Robert Wildin, M.D., promoted to Professor, Joanna Conant, M.D., promoted to Associate Professor, and  Amer Abu Alfa, M.D., promoted to Associate Professor. (6/2024)

Congratulations to Lisa Kapoor on 40 years of service to the pathology department. (6/2024)

Bronwyn Bryant, M.D., Associate Professor, Department of Pathology & Laboratory Medicine, is featured on the People of Pathology Podcast- Episode 181: Redefining Pathology Training With Entrustable Professional Activities. (6/2024)

Pathology resident, Alayna Westcom, M.D., received the Distinguished Medical Student Award from The College of American Pathologists. The award recognizes a fourth-year medical student committed to pursuing pathology residency. (5/2024)

Sharon Mount, M.D., Professor, Department of Pathology & Laboratory Medicine, presented a talk: “Autopsy in the USA: An update and interesting cases from the University of Vermont” at the University of Padua in Padua, Italy on April 22, 2024. (5/2024)Sharon-Padua

Congratulations to Anne Stowman, M.D., assistant professor of pathology and laboratory medicine, on accepting the position as Network Vice Chair for Anatomic Pathology. (3/2024)  

Congratulations to Ashley Volaric, M.D., assistant professor of pathology and laboratory medicine, on receiving a Physician-Scientist Pilot Award through the Translational Global Infectious Disease Research (TGIR Group) for her research on Epstein-Barr virus (EBV) epigenetics of diffuse large B-cell lymphomas in sub-Saharan Africa. (3/2024)

Congratulations to Rebecca Wilcox, M.D., associate dean for faculty affairs, and professor of pathology and laboratory medicine, on receiving The Polaris Award for Outstanding Mentorship, and Dr. Yvonne Janssen-Heininger, Ph.D., on receiving the Gender Equity Outstanding Achievement in Medicine & Science Award at the 5th Annual Celebration of Gender Equity in Medicine and Science Awards. This award honors a Larner College of Medicine faculty or staff member who provides outstanding formal or informal mnetorship for women or gender diverse** college community members. Dr. Wilcox was nominated by Andrea Green, Julie Dumas, Alexandra Kalof, and LE Faricy. (2/2024) **Gender diverse refers to those who identify with a gender outside of the she/her, he/him binary   

Congratulations to Dr. Brian Cunniff, Ph.D., assistant professor of pathology and laboratory medicine, the team in the Cunniff Lab, and industry partner , RS Oncology, on having their novel therapy enter Phase 2 Clinical trials. Read more here Milestone for UVM-developed cancer drug. (2/2024)

During the annual Larner College of Medicine's Foundations Award Celebration, Amer Abu Alfa, M.D., assistant professor of pathology and laboratory medicine received The Dean Warshaw Integration Award recognizing the faculty member whose teaching best captured the spirit of the Vermont Integrated Curriculum. Congratulations. Christina Wojewoda, M.D., professor of pathology and laboratory medicine and vice chair for education pathology, presented the Ephraim Woll Award for Excellence in General Pathology to John Rustad. (2/2024) 

Congratulations Dr. Bei Zhang, M.D., M.S., Ph.D., MLS(ASCP)CM, on January 17, 2024, is to receive the Educational Scholarship Award from the Teaching Academy Awards for Teaching and Educational Excellence. This award recognizes an individual who has demonstrated a record of Quality, Quantity, and Engagement in medical education scholarship. Dr. Zhang, M.D., M.S., Ph.D., MLS(ASCP)CM, has been advanced to Distinguished Educator by the Teaching Academy at LCOM. Congratulations also to Bronwyn Bryant, M.D., for advancing to the level of Master Teacher and Agnes Balla, M.D., on being inducted as a Member. (1/2024)

Congratulations to University Scholar Mary Cushman, M.D., M.Sc., professor of medicine and pathology and laboratory medicine, on being ranked #90 in the U.S. and #144 in the world as one of the Best Female Scientists in the World, by Research.com. Also, Dr. Cushman, M.D., M.Sc., recently delivered the Robert Reneman Lecture at the Cardiovascular Research Institute Maastricht (CARIM)'s 2023 symposium in The Netherlands. The tile of her talk was "Stroke and Cognitive Impairment in a Biracial U.S. Cohort: The REGARDS Study." (1/2024)

In a recent Nature Methods paper, Doug Taatjes, Ph.D., Director of the Microscopy Imaging Center, and the Center for Biomedical Shared Resources at the Larner College of Medicine, together with colleagues from the international consortium QUAREP-LiMi, proposed a set of standardized community-developed checklists to assist researchers, reviewers, and journal editors with the goal of increasing the clarity and reproducibility of image figures and their analyses. The hope is that many journals will adopt these guidelines as part of their “Instructions for Authors”—providing a succinct and easy to use checklist for authors when compiling images for reproduction and descriptions of image analyses performed. (11/2023) (from the LCOM Newsletter)

Congratulations to some of our residents and our fellowship student on having their abstracts accepted for the upcoming 2024 USCAP annual meeting in March. "Unexpected Cardiac Amyloidsis: Demographics, Histology, Distribution and Clinical Significance: A Review of 15 Autopsy Cases." (Jesse Mostoller, Neel Hedge, Nick Taylor). "GATA3 Positive Malignant Spindle Cell Neoplasm Involving the Liver Diagnosed as Metastatic Sarcomatoid Chromophobe Renal Cell Carcinoma at Autopsy." (Rae Nusapan). "Long Term Outcome in a Case of Tetralogy of Fallot Surgically Treated with Palliative Shunts: Findings from an Adult Autopsy." (Dore Guptil, Heather Giguere). (11/2023)

Mark_FungCongratulations to Dr. Mark Fung, M.D., PhD., Professor Pathology and Laboratory Medicine, on receiving the 2023 College of American Pathologists (CAP) Lifetime Achievement Award. Dr. Fung is a nationally recognized expert in transfusion medicine. (10/2023) 

Congratulations to Jessica Crothers, M.D., Assistant Professor Pathology and Laboratory Medicine, on achieving the Notice of Special Interest Team Science award from NIAID for: "Effects of the gut microbiota on oral vaccine response in adults and children." (10/2023)

Nicole BouffardCongratulations to Nicole Bouffard on being awarded the "Scientific Research Staff Award" for 2023. This was presented to Nicole at the September 21, 2023, LCOM Research Excellence Award Ceremony. This is a great honor for Nicole and the Department of Pathology and recognizes her contributions and importance to the department and MIC. (10/2023)

Congratulations to Brian Cunniff, Ph.D., Assistant Professor Pathology and Laboratory Medicine, on being awarded a $1.6 million R01 grant by the National Institute of General Medical Sciences to study the role of mitochondrial trafficking in regulating cell migration, a key feature of metastatic tumors. (9/2023)

Congratulations to Yvonne Janssen-Heininger, Ph.D., Professor Pathology and Laboratory Medicine, on becoming a University of Vermont Cancer Center Program Co-Leader, Cancer Cell. (9/2023)

Congratulations to the following pathology members on receiving research support funds in April 2023. Recipients were: John Kennedy, M.D., $6520 for morphologic and immunohistochemical re-evaluation of renal cell carcinomas exhibiting papillary architecture, with emphasis on tumors demonstrating "type 2" morphology. Yvonne Janssen-Heininger, Ph.D., $15,000 for a joint initiative between RBP, UVM Cancer Center, and faculty in the Department of Chemistry. Megan Tarte $745 for Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease ConferenceAlbert van der Vliet, Ph.D., $14,400 for Redox processes in macrophage activation in IPF. (9/2023)

Congratulations to the following faculty members on their promotions: Vikas Anathy, Ph.D., to Professor with tenure, Bronwyn Bryant, M.D., to Associate Professor, John DeWitt, M.D., Ph.D., to Associate Professor, Sarah Nowak Ph.D., to Associate Professor, and Christi Wojewoda, M.D., to Professor. (6/2023)

Bei Zhang, M.D., M.S., Ph.D., MLS(ASCP), associate professor of pathology and laboratory medicine, did an educational scholarship session titled "Activate Students Learning Outside Classroom." at the 8th International meeting of the Association of Biochemistry Educators. Dr. Zhang also conducted two additional workshops with other ABE members titled "Linking Clinical Presentations to Their Biochemistry: A novel ABE Clinical-Biochemistry Curricular Treat Mapping Educational Tool.", and "Getting to Clerkship and Beyond: Crafting Biochemistry Learning Objectives that Connect and Integrate Basic Science Concepts with Clinical Application." (5/2023)

Congratulations to Dr. Maureen Harmon, M.D., associate professor of pathology and laboratory medicine, and Dr. Amer Abu Alfa, M.D., assistant professor of pathology and laboratory medicine for being recognized by medical students for their professionalism. Dr. Harmon was recognized for social responsibility and Dr. Abu Alfa was recognized for compassion. (5/2023)

Congratulations to Mary Cushman, Ph.D., M.Sc., professor of medicine and pathology and laboratory medicine, on being named a University Distinguished Professor of Medicine, Hematology/Oncology Division, and  Pathology and Laboratory Medicine. (5/2023)

View the story Mammograms of a study by Sarah Nowak, Ph.D., assistant professor of pathology and laboratory medicine, and researchers at the UVM Cancer Center showing data that fewer women being screened for breast cancer. (4/2023)

vandervliet-habibovic420x280A new study by Albert van der Vliet, Ph.D., professor of pathology and laboratory medicine, and a team of University of Vermont (UVM) researchers is honing in on why people with asthma often have worse symptoms if they are obese. This new research demonstrates that the gene DUOX1 likely contributes to the connection between obesity and asthma.  The research was published ahead of print in the American Journal of Physiology-Lung Cellular and Molecular Physiology and was highlighted as an APSselect article for March 2023. Albert van der Vliet, Ph.D., was the senior author on the paper, along with department of pathology and laboratory medicine coauthors Aida Habibovic, lab research technician; Litiele Cruz, Ph.D., visiting scholar; Vikas Anathy, Ph.D., associate professor; University Distinguished Professor Yvonne Janssen-Heininger, Ph.D.; and additional team members and authors from UVM. Read the full LCOM News story LCOM News (4/2023)

Congratulations to Bronwyn Bryant, M.D., Assistant Professor of Pathology and Laboratory Medicine, for having your proposal, Consequential Validity of Entrustable Professional Activities in Pathology Residency Training selected to receive a Frymoyer Scholars Program project of $48,000 to be funded July 1, 2023 through June 30, 2025. (4/2023)

Congratulations to Martin Chang, M.D., Ph.D., on accepting the new role as Vice Chair for Faculty Affairs. (4/2023)

Congratulations to Joanna Conant, M.D., on becoming the new Pathology Student Fellowship Director starting July 1, 2023. (4/2023)

Congratulations to The Cunniff Lab, on receiving funding to support research focused on malignant mesothelioma. The funding was from The Butler Family Foundation Fund for Cancer Research at the University of Vermont Cancer Center. The Butler Fund was established by the Butler family in memory of two loved ones lost to mesothelioma. (03/2023)