Research Overview

researchWe study DNA, RNA, and proteins — analyzing their synthesis and structure as well as their actions and interactions. We use physical techniques that include spectroscopy and crystallography, cell biological techniques including multispectral confocal microscopy and cell sorting, biochemical techniques such as enzyme purification and characterization, along with molecular biological techniques and genetics including single-cell genomic, spatial transcriptomic, and epigenomic analysis.  By attacking problems using these complementary approaches, we have developed a collaborative environment.

Our departmental missions include teaching, scholarship, and research with our faculty funded for their research programs through the NCI, NIAMS, NIDCR, NSF, and BSF. These grants, coupled with our frequent receipt of NIH Shared Instrumentation awards, have allowed us to provide state-of-the-art research instrumentation for our faculty and students. The Biochemistry Department provides leadership for the Northern New England Clinical and Translational Research Network, an NIH funded program that supports clinical and translational research to address the health and healthcare challenges of Northern New England rurality with emphasis on prevention, early detection, treatment, and survivorship of acute and chronic diseases including cancer, cardiovascular disease, metabolic diseases, diabetes, and musculoskeletal disease. The Department of Biochemistry provides leadership for the Vermont Biomedical Research Network, an NIH supported program to develop infrastructure and guidance for Biomedical investigation to educators and undergraduate students throughout Vermont. Our faculty are world-recognized leaders -- several serving as officers in different national and international scientific organizations and others serving as regular study-section members. We are heavily involved in the educational activities of the College, offering numerous courses for graduate, medical and undergraduate students.


Learn more about our faculty’s research here.