Professor of Medicine |
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HSRF Room 228
149 Beaumont Avenue
Burlington, VT 05405
Telephone: (802) 656-8912
Fax: (802) 656-8900 |
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Jason.H.Bates@uvm.edu
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Clinical Expertise
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Monitoring of lung function in patients and animals
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Automatic control of ventilatory support
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Mechanical determinants of bronchial responsiveness
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Education
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1978: B.Sc. (First-class Honours) PHYSICS, Canterbury University, Christchurch, New Zealand, 1978.
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1981: Ph.D. MEDICINE, Otago University, Dunedin, New Zealand
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1994: D.Sc. Canterbury University, Christchurch, New Zealand
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Postdoctoral Training
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1981 - 1982: Post-doctoral Fellow (funded by the Medical Research Council of New Zealand), Department of Medicine, Christchurch Clinical School of Medicine, Christchurch, New Zealand. Supervisor: Prof. D.W. Beaven
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1982 - 1983: Scientific Officer, Department of Medicine, Christchurch Clinical School of Medicine, Christchurch, New Zealand.
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1983 - 1986: Research Fellow, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada. Supervisor: Prof. J. Milic-Emili.
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Professional Societies
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Fellow, American Institute for Medical and Biological Engineering
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I.E.E.E. Biomedical Engineering Society (elected Senior Member)
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American Physiological Society (elected regular member).
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Biomedical Engineering Society
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American Thoracic Society
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Area of Interest
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Lung Mechanics
Asthma and lung injury
Mathematical/computer modeling of physiology
Laboratory instrumentation and measurement
Complexity and emergence in biomedicine
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Publications
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The influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction. M.A. Khan, R. Ellis, M.D. Inman, J. H.T. Bates, M.J. Sanderson, and L.J. Janssen. American Journal of Physiology - Lung Cellular and Molecular Physiology. 299: L98-L108, 2010.
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A multiscale, spatially-distributed model of asthmatic airway hyper-responsiveness. A. Z. Politia, G.M. Donovan, M.H. Tawhai, M.J. Sanderson, A.-M. Lauzon, J.H. T. Bates, and J. Sneyd. Journal of Theoretical Biology. 266: 614-624, 2010.
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Modeling the complex dynamics of derecruitment in the lung. B. Ma, and J.H.T. Bates. Annals of Biomedical Engineering. 38: 3466-3477, 2010
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The temporal variability of dominant frequency and complex fractionated atrial electrograms constrains the validity of sequential mapping in human atrial fibrillation. N. Habel, P. Znojkiewicz, N. Thompson, J.G. Müller, B. Mason, J. Calame, S. Calame, S. Sharma, G. Mirchandani, D. Janks, J.H.T. Bates, A. Noori, A. Karnbach, D.L. Lustgarten, B.E. Sobel, and P. Spector. Heart Rhythm. 7: 586-593, 2010.
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A breath biofeedback computer game for children with cystic fibrosis. P.M. Bingham, J.H.T. Bates, J. Thompson-Figueroa, and T.L. Lahiri. Clinical Pediatrics. 49: 337-342, 2010.
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"Animal models of asthma." J.H.T. Bates, M. Rincon and C.G. Irvin. American Journal of Physiology – Lung, Cell and Molecular Physiology. 297: L401-L410, 2009.
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Transient oscillatory force-length behavior of activated airway smooth muscle. J.H.T. Bates, S.R. Bullimore, A.Z. Politi, J. Sneyd, R.C. Anafi and A-M. Lauzon. American Journal of Physiology – Lung, Cell and Molecular Physiology. 297: L362-L372, 2009.
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“Tumor necrosis factor-a overexpression in lung disease: a single cause behind a complex phenotype.” L.K.A. Lundblad, J. Thompson-Figueroa, T. Leclair, M.J. Sullivan, M.E. Poynter, C.G. Irvin, and J.H.T. Bates. American Journal of Respiratory and Critical Care Medicine. 171: 1363-1370, 2005.
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Peak pressures during manual ventilation.” M. Turki, M.P. Young, S.S. Wagers, and J.H.T. Bates. Respiratory Care. 50: 340-344, 2005.
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“Tumor necrosis factor-a overexpression in lung disease: a single cause behind a complex phenotype.” L.K.A. Lundblad, J. Thompson-Figueroa, T. Leclair, M.J. Sullivan, M.E. Poynter, C.G. Irvin, and J.H.T. Bates. American Journal of Respiratory and Critical Care Medicine. 171: 1363-1370, 2005.
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“Pulmonary impedance and alveolar instability during injurious ventilation in rats.” G.B. Allen, L.A. Pavone, J.D. DiRocco, J.H.T. Bates, and G.F. Nieman. Journal of Applied Physiology. 99: 723-730, 2005.
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“The interface between measurement and modeling of peripheral lung mechanics.” J.H.T. Bates, and K.R. Lutchen. Respiratory Physiology & Neurobiology. 148: 153-164, 2005.
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“Airways hyperresponsiveness induced by cationic proteins in vivo: site of action.” T. Homma, J.H.T. Bates, and C.G. Irvin,. American Journal of Physiology - Lung Cellular and Molecular Physiology. 289: L413-L418, 2005.
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“Modeling the oscillation dynamics of activated airway smooth muscle strips” J.H.T. Bates, and A.-M. Lauzon. American Journal of Physiology - Lung Cellular and Molecular Physiology. 289: L849-L855, 2005.
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“Exaggerated airway narrowing in mice treated with intra-tracheal cationic protein.” J.H.T. Bates, S.S. Wagers, R.J. Norton, L.M. Rinaldi, and C.G. Irvin. Journal of Applied Physiology. 100 : 500-506, 2006.
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“The estimation of lung mechanics parameters in the presence of pathology: A theoretical analysis.“ J.H.T. Bates and G.B. Allen. Annals of Biomedical Engineering. 34: 384-392, 2006.
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“Choosing the Frequency of Deep Inflation in Mice: Balancing Recruitment against Ventilator-Induced Lung Injury.” G.B. Allen, B.T. Suratt, L. Rinaldi, J.M. Petty, and J.H.T. Bates. American Journal of Physiology - Lung Cellular and Molecular Physiology. 291: L710-L717, 2006.
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“Intrinsic and antigen induced airway hyperresponsiveness are the result of diverse physiologic mechanisms.” S. Wagers, H.C. Haverkamp, J.H.T. Bates, R.J. Norton, J.A. Thompson-Figueroa, M.J. Sullivan, and C.G. Irvin. Journal of Applied Physiology. 102: 221-230, 2007.
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“Airways hyperresponsiveness in allergically inflamed mice: the role of airway closure.” L.K.A. Lundblad, J. Thompson-Figueroa, G.B. Allen, L. Rinaldi, C.G. Irvin and J H.T. Bates. American Journal of Respiratory and Critical Care Medicine. 171: 1363-1370, 2007.
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“Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction.” J.H.T. Bates and A.-M. Lauzon. Journal of Applied Physiology. 102: 1912-1920, 2007.
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“Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.” S.S. An. T.R. Bai, J.H.T. Bates, J.L Black, R.H. Brown, V. Brusasco, P. Chitano, L. Deng, M. Dowell, D.H. Eidelman, B. Fabry, N.J. Fairbank, L.E. Ford, J.J. Fredberg, W.T. Gerthoffer, S.H. Gilbert, R. Gosens, S.J. Gunst, A.J. Halayko, R.H. Ingram, C.G. Irvin, A.L. James, L.J. Janssen, G.G. King, D.A. Knight, A.M. Lauzon, O.J. Lakser, M.S. Ludwig, K.R. Lutchen, G.N. Maksym, J.G. Martin, T. Mauad, B.E. McParland, S.M. Mijailovich, H.W. Mitchell, R.W. Mitchell, W. Mitzner, T.M. Murphy, P.D. Paré, R. Pellegrino, M.J. Sanderson, R.R. Schellenberg, C.Y. Seow, P.S.P. Silveira, P.G. Smith, J. Solway, N.L. Stephens, P.J. Sterk, A.G. Stewart, D.D. Tang, R.S. Tepper, T. Tran, L. Wang. European Respiratory Journal. 29: 834-860, 2007.
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“A recruitment model of quasi-linear power-law stress adaptation in biological soft tissue.” J.H.T. Bates. Annals of Biomedical Engineering. 35: 1165-1174, 2007.
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“The response to recruitment worsens with progression of lung injury in a mouse model of acid aspiration.” G.B. Allen, T. Leclair, M. Cloutier, J. Thompson-Figueroa and J.H.T. Bates. American Journal of Physiology – Lung, Cell and Molecular Physiology. 292: L1580-L1589, 2007.
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“Linking parenchymal disease progression to changes in lung mechanical function by percolation.” J.H.T. Bates, G.S. Davis, A. Majumdar, K.J. Butnor and B. Suki. American Journal of Respiratory and Critical Care Medicine. (in press)
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“Lung impedance measurements are more useful than simpler measurements of lung function in animal models of pulmonary disease.” (Pro-Con Debate) J.H.T. Bates. Journal of Applied Physiology. (in press)
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