The Department of Obstetrics, Gynecology and Reproductive Sciences maintains an active program of research that includes both clinical and basic science investigations relevant to women's health. Our research is supported by extramural and intramural funding & derived from a combination of federal, private and pharmaceutical sources.
The research, while under the broad aegis of women's health, is quite diverse, and includes ongoing investigations into the:
- Mechanisms of altered contractility in pre-term labor
- Patterns of fetal growth in health and disease, including preeclampsia
- Hemodynamic and vascular adaptations that occur during pregnancy
- Screening and management of lower genital tract cancers
- Hormonal correlates of sexual function and dysfunction
- Pain relief during childbirth
- Immune function during pregnancy (maternal-fetal recognition and protection)
- Lipid disorders in and treatment of polycystic ovarian syndrome (PCO)
- Mechanisms of cervical ripening and labor
- Effects of estrogen and SERM's on vascular function and stroke outcome
- Angiogenesis and ovarian cancer
Patient-oriented studies are conducted in the University of Vermont Medical Center hospital environment, which includes the 16 bed UVM General Clinical Research Center one of approximately 80 centers nationwide, and an excellent resource for clinical investigations. Basic science investigations are carried out in the Given Building, which is part of the Health Science Research Facility that houses The Robert Larner, M.D. College of Medicine at the University of Vermont. The Department of Obstetrics, Gynecology and Reproductive Sciences occupies approximately 4,000 square feet of space dedicated to laboratory investigation.
The Department is committed to supporting both clinical and basic research, and to the integration of research activity into our educational mission, which includes intern/residency training and fellowship programs in maternal fetal medicine and reproductive endocrinology. In addition, our laboratories host medical students, graduate students, postdoctoral trainees and undergraduates seeking to obtain direct, hands-on student experience in biomedical research. As described in associated links, there are ample opportunities for both student and patient participation in research activity, as well as external and internal funding mechanisms for providing research support.
The research interests of individual faculty and additional information, including recent publications, can be obtained in the faculty bios pages.
Clinical Research is conducted at The University of Vermont Medical Center, including the General Clinical Research Center (GCRC), and includes original investigations initiated by faculty as well as participation in national Phase III trials. Techniques used include the following: Color Doppler ultrasonography, DEXA scans, abdominal CT scans, euglycemic clamps, activity surveys, laparoscopic ovarian diathermy.