Northern New England Clinical & Translational Research (NNE-CTR) successes, events and news.
RNAscope is an RNA in situ detection platform. The RNAscope® Assays are based on the proprietary RNAscope® Technology, enabling RNA target expression analysis within intact cells and tissues with high sensitivity and specificity. The innovative RNAscope® Assay, with in situ hybridization technology to detect mRNA and ncRNA targets of >300bp, was launched in 2011 and marks the foundation of our product portfolio. The proprietary probe design requires an average of 20 Z pairs per target, however a minimum hybridization of 6 Z pairs can be used to obtain a signal.
With over 1,400 publications in peer-reviewed journals, across multiple disciplines, the RNAscope® Assay represents a revolutionary advance in in situ target RNA detection.
The seminar highlighted the basis of RNAscope® Technology and labeling protocols, including troubleshooting tips and examples of labeling with both chromogenic and fluorescent dyes.
Watch the presentation.