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Northern New England Clinical and Translational Research (NNE-CTR) successes, events and news.


Highlights

RNAscope Technology presented by Microscopy Imaging Center

November 29, 2018 by Jennifer Smith

RNAscope is an RNA in situ detection platform. The RNAscope® Assays are based on the proprietary RNAscope® Technology, enabling RNA target expression analysis within intact cells and tissues with high sensitivity and specificity. The innovative RNAscope® Assay, with in situ hybridization technology to detect mRNA and ncRNA targets of >300bp, was launched in 2011 and marks the foundation of our product portfolio. The proprietary probe design requires an average of 20 Z pairs per target, however a minimum hybridization of 6 Z pairs can be used to obtain a signal. With over 1,400 publications in peer-reviewed journals, across multiple disciplines, the RNAscope® Assay represents a revolutionary advance in in situ target RNA detection. The seminar highlighted the basis of RNAscope technology and labeling protocols, including troubleshooting tips and examples of labeling with both chromogenic and fluorescent dyes.

RNAscope is an RNA in situ detection platform.  The RNAscope® Assays are based on the proprietary RNAscope® Technology, enabling RNA target expression analysis within intact cells and tissues with high sensitivity and specificity.  The innovative RNAscope® Assay, with in situ hybridization technology to detect mRNA and ncRNA targets of >300bp, was launched in 2011 and marks the foundation of our product portfolio.  The proprietary probe design requires an average of 20 Z pairs per target, however a minimum hybridization of 6 Z pairs can be used to obtain a signal.

With over 1,400 publications in peer-reviewed journals, across multiple disciplines, the RNAscope® Assay represents a revolutionary advance in in situ target RNA detection.

The seminar highlighted the basis of RNAscope® Technology and labeling protocols, including troubleshooting tips and examples of labeling with both chromogenic and fluorescent dyes.

Watch the presentation.
20181129 RNAScope presentation VT

RNAScope presentation ME audience





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