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The most divine art is that of healing. And if the healing art is most divine, it must occupy itself with the .. 'brain'.. as well as the body; for no creature can be sound so long as the higher part of it is suffering.
- Pythagoras
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Helene Langevin, M.D.
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Associate Professor of Neurology |
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Work Address
University of Vermont, College of Medicine, 89 Beaumont Ave., Given C423, Burlington, Vermont 05405
Phone #: 802-656-1001
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Helene.Langevin@uvm.edu
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Area of Interest
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Mechanisms of acupuncture
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Connective tissue mechanotransduction
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Interactions between connective tissue and nervous system
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Musculoskeketal pain mechanisms
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Education
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1985-1986: Endocrinology and Metabolism Fellow, Johns Hopkins Hospital and Sinai Hospital Baltimore, Maryland
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1982-1985: Intern and Resident in Internal Medicine, Johns Hopkins Hospital, Baltimore, Maryland
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1978-1981: Neuroanatomy and Neurochemistry, MRC Neurochemical Pharmacology Unit, Cambridge, England
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1978: MD, McGill University, Montreal, Canada
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Appointments
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2009-present: Director, Program in Integrative Medicine
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2004-present: Research Associate Professor, Department of Neurology
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Board Certification
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1986: American Board of Internal Medicine: Endocrinology and Metabolism
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1985: American Board of Internal Medicine
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Licensure
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1998-present: Vermont, Acupuncture
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1992-present: Vermont, Medicine
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1986-1992: New York State, Medicine
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Professional Activities
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2002-2005: Co-President, Society for Acupuncture Research, University of Vermont
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Research
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2008-2013: National Center for Complementary and Alternative Medicine RO1 (AT 001121) "Connective tissue mechanotransduction".
Principal Investigator: Helene Langevin, MD
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2007-2011: National Center for Complementary and Alternative Medicine (RO1) Soft tissue biomechanical behavior during acupuncture in low back pain
Principal Investigator: H. Langevin
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2002-2007: National Center for Complementary and Alternative Medicine (RO1) Acupuncture mechanism: mechanotransduction model
Principal Investigator: H. Langevin
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2004: National Center for Complementary and Alternative Medicine SBIR (Phase I) Acupuncture needle torque sensor
Principal Investigator: R. Davis
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2000-2002: National Center for Complementary and Alternative Medicine (R21) Investigation of the Effect of Acupuncture Needling on Connective Tissue using Ultrasound
Principal Investigator: H. Langevin
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1999-2001: National Center for Complementary and Alternative Medicine (RO1) Biomechanical effect of Acupuncture Needling
Principal Investigator: H. Langevin
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Publications
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Bouffard NA, Cutroneo K, Badger GJ, White S, Buttolph T, Ehrlich HP, Langevin HM. Tissue stretch decreases soluble TGF ß1 and Type-1 pro-collagen in mouse subcutaneous connective tissue: evidence from ex vivo and in vivo models. J Cell Physiol 214 (2) 389-395, 2008.
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Langevin HM, Rizzo D, Fox JR, Badger GJ, Wu J, Konofagou EE, Stevens-Tuttle D, Bouffard NA, Krag MH. Dynamic morphometric characterization of local connective tissue network structure using ultrasound. BMC Systems Biology 2007 Jun 5;1:25.
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Storch KN, Taatjes DJ, Boufard NA, Locknar S, Bishop NM, Langevin HM. Alpha smooth muscle actin distribution in cytoplasm and nuclear invaginations of connective tissue fibroblasts. Histochem Cell Biol 127(5)523-530, 2007
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Langevin HM, Bouffard NA, Churchill DL, Badger JG,. Connective tissue fibroblast response to acupuncture: dose-dependent effect of bi-directional needle rotation. Journal of Alternative and Complementary Medicine 13:355-360, 2007.
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Langevin HM, Bouffard NA, Churchill DL, Badger JG,. Connective tissue fibroblast response to acupuncture: dose-dependent effect of bi-directional needle rotation. Journal of Alternative and Complementary Medicine 2007 (In Press)
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Storch KN, Taatjes DJ, Boufard NA, Locknar S, Bishop NM, Langevin HM. Alpha smooth muscle actin distribution in cytoplasm and nuclear invaginations of connective tissue fibroblasts. Histochem Cell Biol 127(5)523-530, 2007
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Langevin HM. Connective tissue: A body-wide signaling network? Med Hypoth 66(6):1074-1077, 2006.
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Langevin HM, Bouffard NA, Badger GJ, Churchill DL, Howe AK. Subcutaneous tissue fibroblast cytoskeletal remodeling induced by acupuncture: evidence for a mechanotransduction-based mechanism. J Cellular Physiol 207(3):767-774, 2006.
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Langevin HM, Storch KS, Cipolla MJ, White SL, Buttholph TR, Taatjes DJ. Fibroblast spreading induced by connective tissue stretch involves intracellular redistribution of a- and ß- actin. Histochem Cell Biol 14:1-9, 2006.
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Ahn A.C., Wu J. Badger G.J., Hammerschlag, R., Langevin H.M. Electrical impedance along connective tissue planes associated with acupuncture meridians. BMC Complement Altern Med 5: 10, 2005.
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Langevin H.M., Bouffard N.A., Badger G.J., Iatridis J.C. Howe A.K. Dynamic fibroblast response to subcutaneous tissue stretch ex vivo and in vivo. American Journal of Physiology-Cell Physiology 288:C747-C756, 2005
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Langevin H.M., Badger, G.J., Povolny B.K., Davis R.T., Johnston A.C., Sherman K.J., Kahn J.R., Kaptchuk, T.J. Yin scores and Yang scores: A new method for quantifying diagnostic patterns in traditional Chinese medicine. J Alt Compl Med 10(2) 389-395, 2004
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Langevin H.M., Konofagou E.E., Badger G.J., Churchill D.L., Fox J.R., Ophir J., Garra B.S. Tissue displacements during acupuncture using ultrasound elastography techniques. Ultrasound in Medicine and Biology 30(9): 1173-1183, 2004.
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Langevin H.M., Cornbrooks C.J., Taatjes T.J. Fibroblasts form a body-wide cellular network. Histochem Cell Biol 122:7-15, 2004
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Iatridis J.C., Wu J., Yandow J.A., Langevin H.M. Subcutaneous tissue mechanical behavior is linear and viscoelastic under uniaxial tension. Connective Tissue Research 44(5): 208-217, 2003.
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Link to PubMed
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