Upcoming Events

Jan 29, 2024Dr. Morgan DeSantis, University of Michigan HSRF 400Noon
Feb 5, 2024Stavroula Mili, NIH NCI HSRF 400Noon


Past Events

Nov. 13, 2023Ben Turk, Ph.D., Yale School of Medicine“Global and Targeted Analysis of Protein Kinase Substrate Specificity.”
Oct. 23, 2023Elias T. Spiliotis, PhD, Department of Cell Biology, University of Virginia School of Medicine
“Spatial control of membrane traffic by microtubule-associated septins.”
Oct. 9, 2023Dylan Burnette, Vanderbilt"Building in vitro and in vivo models to understand cardiac development and disease”
Sept. 25, 2023Christopher Johnson, Mississippi State, Dept of Chemistry"Challenging the Trimeric Model: Reinterpreting Ca2+ Regulation of NaV1.5 Cytoplasmic Domain in Solution" 
Sept 18, 2023Colleen Kelly, Ph.D., Previs Lab, UVMMavacamten enhances myosin exchange by folding soluble myosin molecules.
Aug. 21, 2023Thesis Defense:  Katie Queen“Post-Translational Modifications in the Enzymatic Region of KIF18A Regulate Motor Localization and Function”
May 22, 2023Sarah Abeling - UVMRes-in-Progress seminar
May 15, 2023Justin Paluba - UVMRes-in-Progress seminar
May 8, 2023Dr. Matthew Gage, UMass, LowellSmall changes with big effects:  Lessons learned from the structure of titin.
May 1, 2023Dr. Brandon Bensel - UVMRes-in-Progress seminar
April 17, 2023Dr. Amreen Mughal, UVM PharmacologyRes-in-Progress seminar
March 13, 2023Dr. Michael Cianfrocco, Univ of MichiganPump the brakes: molecular mechanisms to turn off kinesin motors.
Feb. 14, 2023Dr. Kenneth B. Margulies, M.D., Perelman School of Medicine, Univ. Pennsylvania.   Human Heart Tissue as a Translational Research Platform.
Jan 30, 2023Dr. Yale Goldman, UPennSingle molecule, multi-parameter confocal fluorescence spectroscopy shows that DEAD-box RNA helicases DDX3X  and DDX3Y are smart, sex-dependent regulators of stress response and mRNA translation.
Jan 23, 2023Dr. Aikaterini  “Katia” Kontrogianni-Konstantopoulos, 
University of Maryland
Insights into the expanding MYBPC1-associated sarcomeric myopathy with tremor.
Jan 9, 2023Dr. Sam Walcott, WPIBuilding mathematical models to connect molecular and cellular muscle measurements.
Dec. 12, 2022Sean Cleary, Loyola Univ.Dynamic Control of the Cardiac Calcium Pump
Nov 28, 2022Sebastian Duno-Miranda - UVMRes-in-Progress seminar
Nov 11, 2022Dr. Sam Reck-Peterson, UCSDRNA recoding in squid tailors kinesin function for different ocean temperatures.
Nov. 10, 2022Dr. Ben Prosser, U Penn“Cytoskeletal control of cardiac growth and mechanics”
Oct 24, 2022Dr. Deena Snoke - UVMRes-in-Progress seminar
Sept. 19, 2022Dr. Luke Rice, UTSouthwesternLooking under the hood of microtubule dynamics.
Aug. 4, 2022Ph.D. Thesis Defense:  Alisa Cario, Cellular, Molecular, and Biomedical Science Graduate Program. Characterization of Tau Disease-Associated Mutation, R5L, on Microtubule BOund Tau Behavior and Function.
June 6, 2022Ph.D. Thesis Defense:  Alex Thompson,  Cellular, Molecular, and Biomedical Science Graduate Program.   Spatial and Temporal Control of the Kinesin Motors KIF11 and KIF22 in Mitosis.
May 9, 2022Dr. Colleen Kelly - UVMRes-in-Progress seminar
April 18, 2022Dr. Grace Tang-Siegel - UVMRes-in-Progress seminar
March 21, 2022Dr. Brandon Bensel - UVMRes-in-Progress seminar
Feb. 14, 2022Alisa Cario - UVMRes-in-Progress seminar
Jan 24, 2022Dr. Ahmet Yildiz, UC - BerkeleyThe Mechanism and Regulation of Dynein Motility.
Dec. 6, 2021Dr. Marvin Bentley, RPIDirect Delivery and Dendritic Degradation Maintain Axonal Polarity.
Nov. 15, 2021Dr. Charlotte Scarff, Univ. of LeedsThe interacting-heads motif of myosin.
Nov. 8, 2021Dr. Pradeep Luther, imperial College LondonCryo-electron tomography of intact cardiac muscle reveals myosin binding protein-C linking myosin and actin filaments
Nov 1, 2021Dr. Xin Xiang, Uniformed Services Univ of Health Sci. Bethesda, MDFunction and regulation of cytoplasmic dynein - insights from fungal cells.
Oct 4, 2021Dr. Lucie Carrier, Univ. Medical Center, HamburghTargeting the proteolytic system in cardiomyopathies.
Sept 20, 2021Dr. Jonathan Kirk, Loyola Univ.Cardiac Sarcomere Protein Quality control and BAG3:  Repairing the engine with stopping the car.
Sept 13, 2021

Dr. Judith Montag, Hannover
Medical School, Germany


Burst-like transcription of sarcomeric genes and cell-to-cell allelic and contractile imbalance in Hypertrophic Cardiomyopathy.
Aug 17, 2021
Leslie Sepaniac, Ph.D. Thesis Defense
CMB Thesis Defense:  Maintenance of Genomic Stability: Impacts of the loss of KIF18A.
May 24, 2021Katie Queen, UVMPhosphorylation of KIF18A alters its localization and mitotic function.
May 17, 2021Dr. Karyn Esser, Univ. FloridaThe muscle circadian clock: a daily regulator of muscle structure and function.
May 10, 2021Dr. Katherine Schutt, UVM

Investigating KIFBP inhibition of KIF18A across cell cycle stages and cell types.

May 3, 2021Dr. Sarah Heissler, Ohio State Univ.Various Themes of Myosin-2 Regulation. 
April 26, 2021Dr. Christina Gurnett, Washington Univ.

Modeling disease variant to solve the "variant of uncertain significance" problem

March 22, 2021Alex Thompson, UVMCan't Stop, Won't Stop: Mutations in KIF22 Disrupt Anaphase Chromosome Segregation
March 15, 2021Brad Palmer, UVMInorganic  Phosphate Accelerates Cardiac Myofilament Relaxation  in Response to Lengthening.
Dec 14, 2020 Dr. Roger Craig, UMassCryo-EM structure of myosin II: how interactions between myosin’s heads and tail relax muscle and switch off cell motility.
Dec 7, 2020Dr. Jason Botten, Med-Immunology Virus-host interactions.
Nov 2, 2020Dr. Lillian Fritz-Laylin, UMass-AmherstChytrid fungi and our evolving view of cell motility. 
Oct. 26, 2020Sebastian Duno-MirandaSlow-type Myosin Binding Protein-C:  a muscle contraction modulator and beyond.
Oct 19, 2020Sarah Vandal, UVMA novel role for Kntc1 in hedgehog signaling during gonadal and bone development
Oct 12, 2020Tae (TJ) Song, Univ. of CincinnatiFast Myosin Binding Protein-C (fMyBP-C):  its expression and function in skeletal muscle.
Oct 5, 2020Jordan Beach, Loyola University Building Contractility:  How non-muscle cells generate contractile forces.
Sept 28, 2020Brian Cunniff, UVM Pathology & Lab SciencesReal time monitoring of H2O2 levels dependent on sub-cellular mitochondrial dynamics.
Sept 21, 2020Coen Elemans, Univ. of Southern DenmarkAll singing, all-dancing:  The embodied motor control of vocal behavior.
Sept. 14, 2020Alisa Cario, UVM

Understanding the Totaulity of the R5L Mutation on Tau:Microtubule Interactions

May 18, 2020

 M. Yusuf Ali

Single-molecule approaches to probe the regulation of kinesin and dynein-driven cargo transport by adapter protein BicD
May 4, 2020

Carolyn Marquis

KIF18A as a Potential Target for Exploiting Chromosomal Instability in Cancer Cells

April 20, 2020 Brandon BenselJournal Club:  Recent publication from the Gelfand and Sellars groups titled, "Competition between kinesin-1 and myosin-V defines Drosophila posterior determination."
March 9, 2020Thesis Defense:  Dominique LessardNovel Pausing Behavior of the Kinesin-3 Family Member KIF1A is Regulated by Tau.
February 10, 2020

Dr. Shashank Skekhar

Brandeis University

Multicomponent molecular mechanisms regulating cellular rates of actin dynamics
January 27, 2020

Alex Thompson


Journal Club: How do small frogs make small mitotic spindles while large frogs make large spindles?
November 25, 2019

Kristina Godek, Ph.D.

Dartmouth College

Causes and Consequences of Aneuploidy and Chromosomal Instability 
Thurs. November 21, 2019

Chip Asbury, Ph.D.

University of Washington 

Building Kinetochores de novo: Biophysical Investigations of Kinetochore Assembly and Function
Mon. November 4, 2019

Andrea Stavoe

University of Pennsylvania

Dynamics of Neuronal Autophagy During Aging and Neurodegeneration
Mon. October 14, 2019

Adam Hendricks, Ph.D.

McGill University 

Interacellular Traffic Control by the Microtubule Cytoskeleton 
Mon. September 30, 2019

David Barefield, Ph.D.

Northwestern University Feinberg School of Medicine 

The Role of Myosin Binding Protein H-Like in Cardiomyopathy and Arrhythmia