Welcome to the Glass Lab!
In the Glass Lab, we are interested in understanding how epigenetic signaling regulates gene expression, and how alterations in these pathways are involved in disease development, particularly cancer and infectious disease. We are investigating the molecular mechanisms driving the recognition of histone post-translational modifications in order to identify new therapeutic strategies.
The combinations of marks that make up the histone code have been difficult to decipher, and how multiple modifications modulate protein recognition is not well understood. We aim to determine how physiologically abundant combinations of histone modifications regulate chromatin reader activity to influence disease progression. To address our research questions, we use a diversity of approaches in molecular biology, genomics, biochemistry, biophysics, and proteomics.
The Glass lab is located in the Department of Pharmacology in the Larner College of Medicine at the University of Vermont. Dr. Glass is a full member of the UVM Cancer Center and is also a faculty member in the Department of Biochemistry. Follow the Glass lab on Twitter and Facebook!
For those interested in joining our lab, please note that scholarships are available for Ph.D. students.
Glass Lab Current Members:
Margaret Phillips, Postdoctoral Fellow Ajit Singh, Postdoctoral Fellow
Kiera Malone, Ph.D. Student
Brian Boyle, Biochemistry Student Elizabeth Cook, Biochemistry Student
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Mirabella Vulikh Isabelle Kressy