Welcome to the Glass Lab!

In the Glass Lab, we are interested in understanding how epigenetic signaling regulates gene expression, and how alterations in these pathways are involved in disease development, particularly cancer and infectious disease.  We are investigating the molecular mechanisms driving the recognition of histone post-translational modifications in order to identify new therapeutic strategies.

The combinations of marks that make up the histone code have been difficult to decipher, and how multiple modifications modulate protein recognition is not well understood.  We aim to determine how physiologically abundant combinations of histone modifications regulate chromatin reader activity to influence disease progression.  To address our research questions, we use a diversity of approaches in molecular biology, genomics, biochemistry, biophysics, and proteomics.

The Glass lab is located in the Department of Pharmacology in the Larner College of Medicine at the University of Vermont.  Dr. Glass is a full member of the UVM Cancer Center and is also a faculty member in the Department of Biochemistry.  Follow the Glass lab on Twitter and Facebook!


For those interested in joining our lab, please note that scholarships are available for Ph.D. students.


Glass Lab Current Members:


         Margaret Phillips, Ph.D.                        Ajit_Singh_photo -1

Margaret Phillips, Postdoctoral Fellow               Ajit Singh, Postdoctoral Fellow


        Kiera Malone

       Kiera Malone, Ph.D. Student




    Brian Boyle - photo for website reduced                        Elizabeth Cook 

Brian Boyle, Biochemistry Student                   Elizabeth Cook, Biochemistry Student



    Mirabella Vulikh picture cropped and reduced                         Isabelle Kressy cropped and reduced(2)

            Mirabella Vulikh                                                Isabelle Kressy


 Dr. Karen C. Glass

Karen C. Glass, Ph.D.

Associate Professor
Department of Pharmacology
Contact Information        

E-mail: Karen.Glass@med.uvm.edu
Office Location:
Given, Rm C205A

89 Beaumont Ave.

Burlington, VT 05405 









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