News and Events

Dr. Polly Parsons: Looking Back and Moving Forward

On July 11, E.L. Amidon Chair and Professor of Medicine Polly Parsons, M.D., began the transition to her new role as President and CEO of the Alliance for Academic Internal Medicine (AAIM). Dr. Parsons retains her duties as department chair before fully transitioning to her new position on October 1, 2022. We sat down with Dr. Parsons to reflect on her 16 years at the helm of the department, review her accomplishments and consider the department’s growth, struggles and triumphs. Read more >>

Dixon Named 2022-23 University Scholar

Kirkpatrick Presents University Scholar Lecture on Infectious Disease Research

Beth D. Kirkpatrick, M.D., Director of the UVM Vaccine Testing Center (VTC), presented on Combatting Global Infections Diseases: Vaccines and Human Models for the University Scholar lecture hosted by the UVM Graduate College. Dr. Kirkpatrick discussed how faculty researchers at the VTC study human vaccines with the goal of understanding and preventing infectious diseases around the globe, especially in low resource settings. Read more >>

Viridis Montis Challenge Highlights Early-Career Researchers

The Cardiovascular Research Institute of Vermont’s annual Viridis Montis Early Career Investigator Challenge highlighted top cardiovascular research being conducted by early career investigators from across the University of Vermont. Topics presented at the February 2 event included Cardiac remodeling, chronic kidney disease, brain cell energy generation, hypertension and stroke risk, and socioeconomic status and cardiac rehabilitation outcomes. Read more >>

Geriatrics Experts Host Cognitive Impairment Q & A Session

Faculty and Staff News

• Division of General Internal Medicine faculty and residents attended the Society of General Internal Medicine annual meeting April 6-9, in Orlando, Florida. Attendees included Benjamin Depo, M.D., Charles MacLean, M.D., Halle Sobel, M.D., Emily Greenberger, M.D., Elizabeth Carson, M.D., and Vishu Anekondam, M.D. (pictured below) 
  

• Dragos Banu, M.D., assistant professor in the Division of General Internal Medicine, joined the Essex Adult Primary Care Site as the site M.D. leader.
  
  
• Jason Bartsch, Ph. D., assistant professor in the Division of Hospital Medicine, became the Larner College of Medicine Internal Medicine Clerkship Director in April, 2022.
  
  
• Kim Dittus, M.D., Ph.D., associate professor in the Division of Hematology/Oncology, with the assistance from Kate Strotmeyer, Communications and Community Outreach Director for the UVM Cancer Center, Gina Brittain, Marketing Strategist at the UVM Medical Center and Kristie Grover, Ph.D., NBC-HWC, health coach and survivor navigator for the UVM Cancer Center, a newsletter was created for cancer patients. More 10,000 patients receive the newsletter.

• Shea Lambirth, M.D., assistant professor in the Division of Hospital Medicine, was selected to participate in the Larner College of Medicine Teaching Academy’s Medical Education Fellowship Program 2021-2022.

• Chi Chi Lau, M.D., associate professor in the Division of Rheumatology and Clinical Immunology, was elected to serve on the Faculty Senate Curricular Affairs Committee for a three-year term, 2022 – 2025.

• Bonita Libman, M.D., professor in the Division of Rheumatology and Clinical Immunology, was elected to serve on the UVM Health Network Faculty Practice Council for a three-year term 2022-2025
  
  
• Macaulay Onuigbo, M.D., professor in the Division of Nephrology, was selected as Interim Chief of the Division of Nephrology.

• Division of Hospital Medicine faculty Jason Bartsch, Ph. D.., Maria Burnett, M.D., and Carrie Lyon, M.D.,  co-directed the 10th annual UVM Continuing Medical and Interprofessional Education Hospital Medicine Conference January 30-February 1, 2022. The course provided practical approaches to common problems in hospital medicine informed by experts and the latest evidence.

• Four new physicians will be joining the Adult Hospital Medicine Service this summer:
  • Georgia Farrell, M.D.
  • Arjun Fung-Janardhan, M.D.
  • Jonathan Hingre, M.D.
  • Aaron Levit, D.O.
    
• Diego Adrianzen Herrera, M.D., assistant professor in the Division of Hematology/Oncology, was accepted to the American Society of Hematology’s Clinical Research Training Institute (CRTI) and the CRTI Oversight Subcommittee.
  

• Department of Medicine Supervisor Skyler Bailey just published their first book, Heroes in Good Company: L Company, 86th Regiment, 10th Mountain Division 1943-1945. The book turns interviews, letters, memoirs, archived documents and more into a seamless narrative of the wartime experience of one company of mountain troops. 
  
  
• Jean Dejace, M.D., assistant professor in the Division of Infectious Disease, has been appointed fellowship director for the UVM Infectious Disease Fellowship program.
  
  
• Josh Farkas, M.D., associate professor in the Division of Pulmonary Disease and Critical Care Medicine, received the Gold Foundation’s Champions in Humanism Award after being nominated by the Larner College of Medicine’s Gold Humanism Honor Society, in partnership with the UVM Medical Center. The award pays tribute to healthcare professionals for the humanistic care they have displayed through the COVID-19 pandemic. Awardees were recognized on June 10 at the Gold Foundation’s 2021 Annual Gala.
  
  
• Victoria Hart, Ph.D., assistant professor of medicine for the public health program, received the the Larner College of Medicine Teaching Academy’s 2021 Curriculum Development and Scholarship Award for "Development of asynchronous online modules to support medical student education in public health science.”

Awards and Recognition

Larner College of Medicine Awards and Appointments

Diego Adrianzen Herrera, M.D., assistant professor of medicine in the Division of Hematology/Oncology, was invested as the inaugural holder of the Early Career Green and Gold Professor of Medicine. Dr. Adrianzen Herrera was selected for this two-year appointment by a Department of Medicine committee headed by Mary Cushman, M.D., M.Sc., professor and vice chair for emerging researchers. This Department of Medicine-funded professorship is designed to provide funds to strengthen the research program of the most promising assistant professors in their first five years of their faculty appointment and recognizes the excellence and potential of the recipient’s research program.   Read more.

Beth Kirkpatrick M.D., professor and chair of microbiology and molecular genetics, received the Gender Equity Outstanding Achievement in Medicine and Science Award from the UVM Larner College of Medicine. This award recognizes a woman or gender minority faculty member within the Larner College of Medicine who has demonstrated outstanding achievement in medicine and science through research, education or service.

Foundations Celebration Awards

Lee-Anna Burgess, M.D, assistant professor in the Division of Hospital Medicine, received the AMWA Gender Equity Award from the Larner College of Medicine Class of 2024. This award honors a male or female faculty member who promotes a gender-fair environment for the education and training of physicians and gender diversity in the field. In their nominations of Dr. Burgess for the award, students commented that she "is so respected and admired across the medical school and the hospital and is a phenomenal doctor," and that she "made a point to include gender-affirming language and concepts in the NMGI curriculum.”

Andrew Hale, M.D., assistant professor in the Division of Infectious Disease, received two awards from the Larner College of Medicine Class of 2024:

• Above and Beyond Award, which recognizes the faculty member who went above and beyond the call of duty to help the students in their learning objectives.
• Foundations Course Director Award, which recognizes the foundations course director who showed the highest degree of dedication to the successful design and implementation of their course curriculum. Dr. Hale is course director for the foundations course,  Cardiovascular, Renal and Respiratory Systems.

Regional and Local Awards

Gilman Allen III, M.D., professor in the Division of Pulmonary and Critical Care Medicine, and colleagues from the UVM Medical Center won a Lamplighter Award from the New England Society for Healthcare Communications for the video, "We will never be free from it: A doctor's plea to get vaccinated against COVID-19." The Lamplighter Awards recognize outstanding achievements and campaigns produced in healthcare marketing and public relations. View the video >>

Margaret Infeld, M.D., clinical instructor of medicine and fellow in cardiovascular medicine (mentor: Daniel Lustgarten, M.D., Ph.D.), received a 2022 Early Career Research Award from the Cardiovascular Research Institute of Vermont for the project, "Efficacy of Atrial Anti-Tachycardia Pacing Based on Atrial Lead Position."

Cindy Noyes, M.D., associate professor in the Division of Infectious Disease, was awarded the UVM Medical Center Vision award, in recognition of her contributions towards navigating the community through the Covid-19 pandemic.

Kristen Pierce, M.D., professor in the Division of Infectious Disease, received the 2021 Physician Award for Community Service at the Vermont Medical Society Leadership awards. The award was presented in January.

National Awards, Service and Leadership Roles

Diego Adrianzen Herrera, M.D., assistant professor of medicine in the Division of Hematology/Oncology, was accepted for participation in the Clinical Research Training Institute from the American Society of Hematology, Junior Faculty Awardee. Additional,ly Dr. Adrianzen Herrera received the Hemophilia and Thrombosis Society’s Mentored Research Award.

Molly Barry, M.D., assistant professor in the Division of Hematology/Oncology, was selected to join the ASCO Education Scholars Program 2021-2022.

Jason Bates, Ph.D., Dsc, professor in the Division of Pulmonary Disease and Critical Care Medicine, received the 2022 Robert Crapo Memorial Lifetime Achievement Award in Pulmonary Diagnostics from the American Thoracic Society. This award recognizes a lifetime of achievement in the use of pulmonary function testing, diagnostics, standardization and application. Dr. Bates is a Fellow of the American Thoracic Society.

Mary Cushman, M.D., M.Sc., professor in the Division of Hematology/Oncology, joined the Executive Committee of Local Organizing Committee, 2023 International Society on Thrombosis and Haemostasis Congress, Montreal, Quebec, Canada.

David Kaminsky, M.D., professor in the Division of Pulmonary and Critical Care Medicine, received a Presidential Citation from the American Thoracic Society.

Allen Mead, Director, Department of Medicine, was elected Treasurer of the Alliance for Academic Internal Medicine.

2022 Department of Medicine Faculty Awards

Education News

New Doctoral Degree Candidate

Roz King, M.S.N., R.N., Research Program Manager in Emergency Medicine and Director, Emergency Medicine Research Associate Program in the UVM Department of Surgery, enrolled in the doctoral program in Clinical and Translational Science. Her research interest is in community outreach to prevent overuse of the Emergency Room.

Several students in the Dr. Jason Botton Lab received awards related to their research:

• Cellular, Molecular and Biological Science pre-doctoral students Annalis Whitaker and Inessa Maneulyan received travel awards to present their research at the 2022 American Society of Virology meetings. 
• Postdoctoral Fellow Rebekah Honce, Ph.D., received a Best Poster Award at the 2021 New England Immunology Conference.
  

New Residents and Fellows

The Department of Medicine welcomes our new residents and fellows for 2022-2023.

New Medicine Residents

Internal Medicine
Dr. Steven Bair
Dr. Sara Brennan
Dr. Erika Dorff
Dr. Jesse Evensky
Dr. Jacob Gabbay
Dr. Aaron Henry
Dr. Jennifer Liao
Dr. William Lorentzen
Dr. Margaret MacPhail
Dr. Tessalyn Morrison
Dr. Aaron O’Brien
Dr. Kayla Sturtevant
Dr. Amelia Winter
Dr. Albert Wu
Dr. Jonathan Zeitler

Dermatology
Dr. Blake Boudreax
Dr. Cheyenne Hornback
Dr. Sabrina Bennett

Preliminary
Dr. Ethan Bent - Radiology
Dr. Sheridan Joseph - Dermatology
Dr. Claudia Russell – Physical Medicine & Rehabilitation

Preliminary Neurology
Dr. Samantha (Sam) Blum
Dr. Callie Brown
Dr. Taylor Lakusta-Wong
Dr. Adam Morehead
Dr. Sabrina Wirth

Preliminary Anesthesia
Dr. Alisha Booms
Dr. Sarah “Sally” Clark
Dr. Ryan Dwosh
Dr. Christopher Frederick
Dr. Jefferson Last
Dr. Anna Quinlan

New Medicine Fellows

In the Media

Shahid Ahmed, M.D., assistant professor of medicine in the Division of Hematology/Oncology, was interviewed by Cancer Today in April 2021 in regards to the use of immunotherapy.

Mary Cushman, M.D., M.Sc., professor of medicine in the Division of Hematology/Oncology, was interviewed for the following media publications:

• Healio: "Benefit of full-dose heparin for patients with COVID-19 warrants ‘new standard of care," July 2021. 
• News Medical: "Early anticlotting therapy offers benefits for moderately ill patients with Covid-19," July2021.
• Pharmacy Times: "Early Anticoagulant Treatment Found to Reduce Death in Moderately Ill COVID-19 Patients," July 2021.

Randall Holcombe, M.D., weighed in on a Seven Days article, “Colchester’s Vernal Biosciences Manufactures the mRNA That’s Revolutionizing Medicine,” August 25, 2021.

Sherrie Khadanga, M.D., assistant professor in the Division of Cardiovascular Medicine, was featured on WCAX-TV Channel 3 (CBS) for Heart Month. View the feature story that aired on February 9, 2022. 

Timothy Lahey, M.D., professor of medicine in the Division of Infectious Disease and director of clinical ethics, has graciously taken on "the face of infectious disease" in the media with concerns addressing the pandemic. Dr. Lahey has been featured in multiple local, regional and national media outlets, including multiple interviews on WCAX-TV Channel 3.

Bonita Libman, M.D., professor in the Division of Rheumatology and Clinical Immunology, was interviewed and quoted for an on-line lay-person publication called Creaky Joints, twice:  

• “Tenosynovitis” review with Barbara Brody, for CreakyJoints.org, August 2021.
• “Quality of Life and Arthritis” review with Barbara Brody, for CreakyJoints.org, November 2021. 

Constance van Eeghen, DrPH, assistant research professor in the Division of General internal Medicine Research, was featured in an article, titled “Spotlight on University of Vermont & State Agricultural College – Project: A PCOR/CER Partnering Guide,” in Engagement Award Digest 2021, a publication of the Patient-Centered Outcomes Research Institute.

Division of Cardiovascular Medicine

Khadanga S, Savage PD, Pecha A, Rengo J, Ades PA. Optimizing Training Response for Women in Cardiac Rehabilitation: A Randomized Clinical Trial. JAMA Cardiol. 2022 Feb 1;7(2):215-218. doi: 10.1001/jamacardio.2021.4822. PMID: 34817540; PMCID: PMC8613699.

Ades PA, Khadanga S, Savage PD, Gaalema DE. Enhancing participation in cardiac rehabilitation: Focus on underserved populations. Prog Cardiovasc Dis. 2022 Jan-Feb;70:102-110. doi: 10.1016/j.pcad.2022.01.003. Epub 2022 Jan 31. PMID: 35108567; PMCID: PMC9119375.

Gaalema DE, Yant B, Khadanga S, Savage PD, Rengo JL, Ades PA. Carbon monoxide monitoring to objectively measure smoking status in cardiac rehabilitation. Health Psychol. 2022 Apr 7. doi: 10.1037/hea0001178. Epub ahead of print. PMID: 35389691.

Division of Dermatology

Veerabagu SA, Perz AM, Lukowiak TM, Lee MP, Neal D, Aizman L, Miller CJ, Golda N, Albertini J, Bar A, Leitenberger J, Maher I, Sobanko JF, Chen D, Hollmig T, Aasi S, Sutton A, Higgins HW, Shin TM, Weinberger C, Mattox A, Wysong A, Nugent ST. Etzkorn JR..  Patient reported nasal function and appearance after interpolation flap repair following skin cancer resection: a multi-center prospective cohort study. Facial Plastic Surgery & Aesthetic Medicine, accepted Feb 2022.

Shea K, Potter K, Weinberger C.  Repair of a large cheek defect.  Dermatologic Surgery July 2021, epub ahead of print. PMID: 34313637 .

Alniemi DT, Weinberger CH.  Repair of an extensive forehead, scalp, and eyelid defect. Dermatologic Surgery Mar 2022:48(3):349-351. PMID:  34537787.

Lukowiak TM, Perz AM, Veerabagu SA, Lee MP, Neal D, Alzman L, Miller CJ, Golda  N, Albertini JG, Holmes T, Bar A, Leitenberger J, Maher IA, Sobanko JF, Chen D, Aasi S, Sutton A, Higgings HW, Shin TM, Weinberger C, Mattox A, Wysong A, Etzkorn JR. Patient quality of life after interpolated flap repair of nasal Mohs surgery defects: a multicenter prospective cohort study.  JAMA Dermatology Oct 2021:157(10):1213-6. PMID: 34431977.

Shea K, Weinberger C.  Alarotomy to increase visualization during Mohs micrographic surgery of a squamous cell carcinoma of the nasal septum and sill. Dermatologic Surgery Aug 2021:47(8):1121-2.

Division of Gastroenterology and Hepatology

Sonja P. Dawsey, Pamela M. Vacek, Eric K. Ganguly, Patient and Endoscopic Characteristics of Postcolonoscopy Colon Cancer—A Case-control Study,Gastro Hep Advances, Volume 1, Issue 3, 2022, Pages 277-286, ISSN 2772-5723, https://doi.org/10.1016/j.gastha.2022.01.001.

Hale AJ, Mathur S, Dejace J, Lidofsky SD. Statewide Assessment of the Hepatitis C Virus Care Cascade for Incarcerated Persons in Vermont. Public Health Reports. March 2022. doi:10.1177/00333549221077070

Division of General Internal Medicine Research

Bonnell LN, Crocker AM, Kemp K, Littenberg B. The Relationship Between Social Determinants of Health and Functional Capacity in Adult Primary Care Patients With Multiple Chronic Conditions. Journal of the American Board of Family Medicine July 2021, 34 (4) 688-697; DOI: https://doi.org/10.3122/jabfm.2021.04.210010

Ramos-Nino ME, MacLean CD, Littenberg B. Association between prevalence of obstructive lung disease and obesity: results from the Vermont Diabetes Information System. Asthma Research and Practice 2021; 7:6. https://doi.org/10.1186/s40733-021-00073-1

Ramos-Nino ME, MacLean CD, Littenberg B. Association between Obstructive Lung Disease and Cardiovascular Disease: Results from the Vermont Diabetes Information System. Journal of Respiration. 2021;1: 165-72. https://www.mdpi.com/2673-527X/1/3/16

Hitt JR, Brennhofer SA, Martin MP, Macchi CR, Mullin D, van Eeghen C, Littenberg L, Kessler RS. Further Experience with the Practice Integration Profile A Measure of Behavioral Health and Primary Care Integration. J Clin Psychol Med Settings. 2021 Aug 9. https://doi.org/10.1007/s10880-021-09806-z. PMID: 34370184.

Clifton J, Bonnell L, Hitt J, Crocker A, Rose GL, van Eeghen C, Kessler R, Stephens KA, Teng K, Leon J, Mollis B, Littenberg B. Differences in Occupational Burnout Among Primary Care Professionals: A Cross-Sectional Study. Journal of the American Board of Family Medicine 2021 Nov-Dec;34(6):1203-1211. doi: 10.3122/jabfm.2021.06.210139. PMID: 34772775.

Bonnell LN, Troy, AR, Littenberg B. Nonlinear relationship between nonresidential destinations and body mass index across a wide range of development. Preventive Medicine 2021; 153:106775. doi: 10.1016/j.ypmed.2021.106775. PMID: 34437875

Thoms BL, Gosselin J, Libman B, Littenberg B, Budd R. Efficacy of Combination Therapy With The JAK Inhibitor Baricitinib In The Treatment of COVID-19.  Res Sq [Preprint]. 2021 Sep 8:rs.3.rs-835734. doi: 10.21203/rs.3.rs-835734/v1. PMID: 34518834; PMCID: PMC8437315. SN Comprehensive Clinical Medicine 2022 2022;4(1):42. doi:10.1007/s42399-022-01121-4. Epub 2022 Jan 21. PMID: 35079694.

Ramos-Nino M, MacLean CD, Littenberg B. Potential enhanced association between obstructive lung disease and history of depression in patients with diabetes. Interv Pulmonol 2021; 1(1):1-4. PMC8783552.

Rose G, Bonnell LN, O'Rourke-Lavoie JB, van Eeghen C, Reynolds P, Pomeroy D, Clifton J, Scholle SH, Natkin LW, Callas P, Hitt JR, Crocker AM, Littenberg B. Development and Validation of the Patient Centeredness Index for Primary Care. J Clin Nursing 2022 https://doi.org/10.1111/jocn.16177

Ades S, Pullari B, Holmes CE, Lal I, Kumar S, and Littenberg B. Risk factors for venous thromboembolism in metastatic colorectal cancer with contemporary treatment: A SEER-Medicare analysis. Cancer Medicine 2022;11:1817-26. https://doi.org/10.1002/cam4.4581

Crocker, A.M., Kessler, R., van Eeghen, C., Littenberg, B., et al. Integrating Behavioral Health and Primary Care (IBH-PC) to improve patient-centered outcomes in adults with multiple chronic medical and behavioral health conditions: study protocol for a pragmatic cluster-randomized control trial. Trials 22, 200 (2021). https://doi.org/10.1186/s13063-021-05133-8

van Eeghen, C., Hitt, J., Pomeroy, D., Reynolds, P., Rose, G.L., Lavoie, J. Co-creating the Patient Partner Guide by a Multiple Chronic Conditions Team of Patients, Clinicians, and Researchers: Observational Report. Journal of General Internal Medicine. Mar 2022 DOI: 10.1007/s11606-021-07308-0 

Division of Hematology/Oncology

DeSancho M, Muss JE, Billett HH, Cheng D, Holmes C, Jaffray J, Malone M, Patel K, Sharathkumar A, Thornburg CD, Wang M, Watson C, Rajpurkar M, Study Investigators. Transition of care for pediatric and adult patients with venous thromboembolism: A National Quality Improvement Project from the American Thrombosis and Hemostasis Network (ATHN). Thromb Res. 2021 Apr;200:23-29. doi: 10.1016/j.thromres.2021.01.001. PMID: 33517168

Chen C, Xun P, Unverzagt F, McClure LA, Irvin MR, Judd S, Cushman M, He K. Serum magnesium concentration and incident cognitive impairment: the Reasons for Geographic and Racial Differences in Stroke study. Eur J Nutr. 2021 Apr;60(3):1511-1520. doi: 10.1007/s00394-020-02353-7. PMID: 32737612 

Oni E, Ogunmoroti O, Allen N, A-Mallah MH, Blankstein R, Martin SS, Zeb I, Cushman M, Joshi PH, Budoff MJ, Blaha MJ, Blumenthal RS, Veledar E, Nasir K. Life’s Simple 7 and non-alcoholic fatty liver disease: the Multi-Ethnic Study of Atherosclerosis. Am J Med. 2021 Apr;134(4):519-525. doi: 10.1016/j.amjmed.2020.09.023. PMID: 33285128

Talasaz AH, Sadeghipour P, Kakavand H, Aghakouchakzadeh M, Kordzadeh-Kermani E, Van Tassell BW, Gheymati A, Ariannejad H, Hosseini SH, Jamalkhani S, Sholzberg M, Monreal M, Jimenez D, Piazza G, Parikh SA, Kirtane AJ, Eikelboom JW, Connors JM, Hunt BJ, Konstantinides SV, Cushman M, Weitz JI, Stone GW, Krumholz HM, Lip GYH, Goldhaber SZ, Bikdeli B. Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Apr;77(15):1903-1921. doi: 10.1016/j.jacc.2021.02.035. PMID: 33741176

Carson AP, Long DL, Cherrington AL, Dutton GR, Howard VJ, Brown TM, Howard G, Safford MM, Cushman M. Sex differences in factors contributing to the racial disparity in diabetes risk. Am J Prev Med. 2021 Apr;60(4):e169-e177. doi: 10.1016/j.amepre.2020.09.016. PMID: 33279367

Dibaba DT, Cheng C, Liping L, Bidulescu A, Fly AD, Xun P, Judd SE, Cushman M, He K. Magnesium intake is inversely associated with risk of metabolic syndrome in the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study. Clin Nutr. 2021 Apr;40(4):2337-2342. doi: 10.1016/j.clnu.2020.10.024. PMID: 33129598

Thibord F, Song, Pattee J, Rodriguez B, Chen MH, O’Donnell CJ, Kleber ME, Delgado GE, Guo X, Yao J, Taylor KD, Ozel AB, Brody JA, McKnight B, Gyorgy B, Simonsik E, Leonard HL, Carrasquilla GD, Guindo-Martinez M, Silveira A, Temprano-Sagrera G, Yanek LR, Becker DM, Mathias RA, Becker LC, Raffield LM, Kilpelainen TO, Grarup N, Pedersen O, Hansen T, Linneberg A, Hamsten A, Watkins H, Sabater-Lleal M, Nalls MA, Tregouet DA, Morange PE, Psaty BM, Tracy RP, Smith NL, Desch KC, Cushman M, Rotter JI, de Vries PS, Pankratz ND, Folsom AR, Morrison AC, Marz W, Tang W, Johnson AD. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer. J Thromb Haemost. 2021 Apr 20. doi: 10.1111/jth.15345. PMID: 33876560

Harrington L, Ehlert AN, Thacker EL, Jenny NS, Lopez O, Cushman M, Fitzpatrick A, Mukamal KJ, Jensen MK. Hemostatic factor levels and cognitive decline in older adults: the Cardiovascular Health Study. J Thromb Haemost 2021 May;19(5):1219-1227. doi: 10.1111/jth.15300. PMID: 33725412

Hu Y, Stilp AM, McHugh CP, Rao S, Jai D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, Moon JY, de Vries PS, Hobbs BD, Sun Q, Surendran P, Brody JA, Blackwell TW, Choquet H, Ryan K, Duggirala R, Heard-Costa N, Wang Z, Chami N, Preuss MH, Min N, Ekunwe L, Lange LA, Cushman M, Faraday N, Curran JE, Almasy L, Kundu K, Smith AV, Gabriel S, Rotter JI, Fornage M, Lloyd-Jones DM, Vasan RS, Smith NL, North KE, Boerwinkle E, Becker LC, Lewis JP, Abecasis GR, Hou L, O'Connell JR, Morrison AC, Beaty TH, Kaplan R, Correa A, Blangero J, Jorgenson E, Psaty BM, Kooperberg C, Walton RT, Kleinstiver BP, Tang H, Loos RJF, Soranzo N, Butterworth AS, Nickerson D, Rich SS, Mitchell BD, Johnson AD, Auer PL, Li Y, Mathias RA, Lettre G, Pankratz N, Laurie CC, Laurie CA, Bauer DE, Conomos MP, Reiner AP; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program. Am J Hum Genet.2021 May 6;108(5):874-893. doi: 10.1016/j.ajhg.2021.04.003. PMID: 33887194

Nicoli CD, Plante TB, Long DL, Judd SE, McClure LA, Arora P, Cushman M. N-terminal pro-B-type natriuretic peptide and longitudinal risk of hypertension. Am J Hypertens 2021 May 22;34(5):476-483. doi: 10.1093/ajh/hpaa224. PMID: 33378421

Nicoli CD, Carson AP, Plante TB, Long DL, McClure LA, Schulte J, Cushman M. Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort. J Clin Endocrinol Metab. 2021 May 20;dgab355. doi: 10.1210/clinem/dgab355. PMID: 34013344

Omran SS, Hartman A, Zakai NA, Navi BB. Thrombophilia Testing After Ischemic Stroke: Why, When, and What? Stroke. 2021 May;52(5):1874-1884. doi: 10.1161/STROKEAHA.120.032360. PMID: 33874743

Short SA, Gupta S, Brenner SK, Hayek SS, Srivastava A, Shaefi S, Singh H, Wu B, Bagchi A, Al-Samkari H, Dy R, Wilkinson K, Zakai NA, Leaf DE, STOP-COVID Investigators d-dimer and Death in Critically Ill Patients  With Coronavirus Disease 2019. Crit Care Med. 2021 May 1;49(5):e500-e511. doi: 10.1097/CCM.0000000000004917. PMID: 33591017

Wiercioch W, Nieuwlaat R, Dahm P, Iorio A, Mustafa RA, Neumann I, Rochwerg B, Manja V, Alonso-Coello P, Ortel TL, Santesso N, Vesely SK, Akl EA, Schunemann HJ, Bates SM, Cuker A, Lim W, Monagle P, Kunkle R, Witt DM, Kahn SR, McLintock C, Rezende SM, Zakai NA, ASH VTE Panels Working Group. Development and application of health outcome descriptors facilitated decision-making in the production of practice guidelines. J Clin Epidemiol. 2021 May 13;S0895-4356(21)00139-6. doi: 10.1016/j.jclinepi.2021.04.016 PMID: 33992716

Tejera CH, Minnier J, Fazio S, Safford MM, Colantonio LD, Irvin MR, Howard V, Zakai NA, Pamir N. High triglyceride to HDL cholesterol ratio is associated with increased coronary heart disease among White but not Black adults. Am J Prev Cardiol. 2021 May 20;7:100198. doi: 10.1016/j.ajpc.2021.100198. PMID: 34611638

MacLehose RF, Zakai NA, Walker RF, Alonso A, Adams T, Lutsey PL. Impact of oral anticoagulant choice for the secondary prevention of venous thromboembolism on the risk of inpatient bleeding. Res Pract Thromb Haemost. 2021 May 4;5(4):e12514. doi: 10.1002/rth2.12514. PMID: 33977213

Stanislawski MA, Lange LA, Raffield LM, Zakai NA, Meyer M, Ferrier K, Szeto MD, Leavitt C, Shortt JA, Thornton TA, Tracy RP, Auer PL, Reiner AP, Lange EM, Olson NC. Soluble CD14 Levels in the Jackson Heart Study: Associations with Cardiovascular Disease Risk and Genetic Variants. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e378. doi:10.1161/ATVBAHA.121.316035. PMID: 33910371

Yi SY, Steffen L, Cushman M, Folsom AR, Lutsey PL. Contrasting associations of prudent and western dietary patterns with risk of developing venous thromboembolism. Am J Med 2021 Jun;134(6):763-768.e3. doi: 10.1016/j.amjmed.2021.01.016. PMID: 33609530

Camidge DR, Otterson GA, Clark JW, Ignatius Ou SH, Weiss J, Ades S, Shapiro GI, Socinski MA, Murphy DA, Conte U, Tang Y, Wang SC, Wilner KD, Villaruz LC. Crizotinib in Patients with MET-Amplified NSCLC. J Thorac Oncol. 2021 Jun;16(6):1017-1029. doi: 10.1016/j.jtho.2021.02.010. PMID: 33676017

Mughal A, Wahlberg KJ, Li Z, Flyer JN, Olson NC, Cushman M. Impact of an institutional grant award on early career investigator applicants and peer reviewers. Res Pract Thromb Haemost 2021 Jun 27;5(5);e12555. doi: 10.1002/rth2.12555. PMID: 34263104

Wang H, Rosendaal FR, Cushman M, van Hylckama Vlieg A. D-dimer, thrombin generation, and risk of a first venous thrombosis in the elderly. Res Pract Thromb Haemost 2021 Jun 21,5(5):e12536. doi: 10.1002/rth2.12536. PMID: 34263100

Jehangir W, Karabachev A, Tsao J, Anker CJ, Garapati SS, Kikut JK, Rehman HT. Metastatic Malignant Parganglioma Presenting as a Neck Mass Treated with Radiolabeled Somatostatin Analog. Case Rep Oncol Med. 2021 Jun 7;2021:8856167. doi: 10.1155/2021/8856167. PMID: 34211793

Tolaney SM, Kalinsky K, Kaklamani V, D’Adamo DR, Aktan G, Tsai ML, O’Regan RM, Kaufman PA, Wilks ST, Andreopoulou E, Patt DA, Yuan Y, Wang G, Savulsky C,Xing D, Kleynerman E, Karantza V, Diab S. Eribulin Plus Pembrolizumab in Patients with Metastatic Triple-Negative Breast Cancer (ENHANCE 1): A Phase Ib/II Study. Clin Cancer Res. 2021 Jun 1;27(11):3061-3068. doi: 10.1158/1078-0432.CCR-20-4726. PMID: 33727258

Kaufman PA, Hurvitz SA, O’Shaughnessy J, Mason G, Yardley DA, Brufsky AM, Rugo HS, Cobleigh M, Swain SM, Tripathy D, Morris A, Antao V, Li H, Jahanzeb M. Baseline characteristics and first-line treatment patterns in patients with HER2-positive metastatic breast cancer in the SystHERs registry. Breast Cancer Res Treat. 2021 Jul;188(1):179-190. doi: 10.1007/s10549-021-06103. PMID: 33641083

Parikh NS, Koh I, VanWagner LB, Elkind MSV, Zakai NA, Cushman M. Liver Fibrosis is Associated with Ischemic Stroke Risk in Women but not Men: The REGARDS Study. J Stroke Cerebrovasc Dis 2021 Jul;30(7):105788. doi:  10.1016/j.jstrokecerebrovasdis.2021.105788. PMID: 33866274

Mukaz DK, Dawson E, Howard VJ, Cushman M, Higginbotham JC, Judd SE, Kissela BM, Safford MM, Soliman EZ, Howard G. Rural/urban differences in the prevalence of stroke risk factors: A cross-sectional analysis from the REGARDS study. J Rural Health. 2021 Jul 16;10.1111/jrh.12608. doi: 10.1111/jrh.12608. PMID: 34270125

Khialani D, Vasan S, Cushman M, Dahm AEA, Sandset PM, Rossouw J, van Hylckama Vlieg A. Venous thrombosis with oral postmenopausal hormone therapy: roles of activated protein C resistance and tissue factor pathway inhibitor. J Thromb Haemost 2021 Jul;19(7):1729-1737. doi: 10.1111/jth.15319. PMID: 33774921

Evensen LH, Folsom AR, Pankow JS, Hansen JB, Allison MA, Cushman M, Lutsey PL. Hemostatic factors, inflammatory markers and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis. J Thromb Haemost  2021 Jul;19(7):1718-1728. doi: 10.1111/jth.15315. PMID: 33773045

Valderrabano RJ, Buzkova P, Chang P-Y, Zakai NA, Fink HA, Robbins JA, Wu JY, Lee JS, Cardiovascular Health Study group. Associations of hemoglobin and change in hemoglobin with risk of incident hip fracture in older men and women: the cardiovascular health study. Osteoporos Int. 2021 Aug;32(8):1669-1677.  doi: 10.1007/s00198-021-05873-y. PMID: 33576845

Zakai NA, Walker RF, MacLehose RF, Koh I, Alonso A, Lutsey PL. Venous thrombosis recurrence risk according to warfarin versus direct oral anticoagulants for the secondary prevention of venous thrombosis. Res Pract Thromb Haemost. 2021 Aug 17;5(6):e12575. doi: 10.1002/rth2.12575. PMID: 34430789

Singleton MJ, Yuan Y, Dawood FZ, Howard G, Judd SE, Zakai NA, Howard VJ, Herrington DM, Soliman EZ, Cushman M. Multiple blood-biomarkers and stroke risk in atrial fibrillation: the REasons for Geographic And Racial Differences in Stroke study. J Am Heart Assoc 2021 Aug 3;10(15):e020157. doi: 10.1161/JAHA.120.020157. PMID: 34325516

Thibord F, Song C, Pattee J, Rodriguez BAT, Chen MH, O'Donnell CJ, Kleber ME, Delgado GE, Guo X, Yao J, Taylor KD, Ozel AB, Brody JA, McKnight B, Gyorgy B, Simonsick E, Leonard HL, Carrasquilla GD, Guindo-Martinez M, Silveira A, Temprano-Sagrera G, Yanek LR, Becker DM, Mathias RA, Becker LC, Raffield LM, Kilpeläinen TO, Grarup N, Pedersen O, Hansen T, Linneberg A, Hamsten A, Watkins H, Sabater-Lleal M, Nalls MA, Trégouët DA, Morange PE, Psaty BM, Tracy RP, Smith NL, Desch KC, Cushman M, Rotter JI, de Vries PS, Pankratz ND, Folsom AR, Morrison AC, März W, Tang W, Johnson AD. FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer. J Thromb Haemost 2021 Aug;19(8):2019-2028. doi: 10.1111/jth.15345. PMID: 33876560

Nicoli CD, Carson, AP, Plante TB Long DL, McClure LA, Schulte J, Cushman M. Pro-neurotensin/neuromedin N and risk of incident metabolic syndrome and diabetes mellitus in the REGARDS cohort. J Clin Endocrinol Metab 2021 Aug 18;106(9):e3494. doi: 10.1210/clinem/dgab355. PMID: 34013344

Plante TB, Long DL, Guo B, Howard G, Carson AP, Howard VJ, Judd SE, Jenny NS, Zakai NA, Cushman M. C-reactive protein and hypertension incidence in black and white Americans: REasons for Geographic And Racial Differences in Stroke (REGARDS) study. Am J Hypertension 2021 Aug 9;34(7):698-706. doi: 10.1093/ajh/hpaa215. PMID: 33326556

REMAP-CAP Investigators; ACTIV-4a Investigators; ATTACC Investigators; Goligher EC, Bradbury CA, McVerry BJ, Lawler PR, Berger JS, Gong MN, Carrier M, Reynolds HR, Kumar A, Turgeon AF, Kornblith LZ, Kahn SR, Marshall JC, Kim KS, Houston BL, Derde LP, Cushman M, Tritschler T, Angus DC, Godoy LC, McQuilten Z, Kirwan BA, Farkouh ME, Brooks MM, Lewis RJ, Berry LR, Lorenzi E, Gordon A, Ahuja T, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Contreras A, Costantini TW, de Brouwer S, Detry MA, Duggal A, Dzavik V, Effron MB, Eng HF, Escobedo J, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, Fowler RA, Froess JD, Fu Z, Galanaud JP, Galen BT, Gandotra S, Girard TD, Goodman AL, Goossens H, Green C, Greenstein YY, Gross PL, Haniffa R, Hedge SM, Hendrickson CM, Higgins AM, Hindenburg AA, Hope AA, Horowitz JM, Horvat CM, Huang DT, Hudock K, Hunt BJ, Husain M, Hyzy RC, Jacobson JR, Jayakumar D, Keller NM, Khan A, Kim Y, Kindzelski A, King AJ, Knudson MM, Kornblith AE, Kutcher ME, Laffan MA, Lamontagne F, Le Gal G, Leeper CM, Leifer ES, Lim G, Lima FG, Kinstrum K, Litton E, Lopez-Sendon J, Lother SA, Marten N, Marinez AS, Martinez M, Garcia EM, Mavromichalis S, McAuley DF, McDonald EG, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Mouncey PR, Murthy S, Nair GB, Nair R, Nichol AD, Nicolau JC, Nunez-Garcia B, Park JJ, Park PK, Parke RL, Parker JC, Parnia S, Paul JD< Pompilio M, Quigley JG, Rosenson RS, Rost NS, Rowan K, Santos FO, Santos M, Santos MO, Satterwhite L, Saunders CT, Schreiber J, Schutgens RE, Seymour CW, Siegal DM, Silva Jr DG, Singhal AB, Slutsky AS, Solvason D, Stanworth SJ, Turner AM, van Bentum-Puijk W, van de Veerdonk FL, van Diepen S, Vazquez-Grande G, Wahid L, Wareham V, Widmer RJ, Wilson JG, Yuriditsky E, Zhong Y, Berry SM, McArthur CJ, Neal MD, Hochman JS, Webb SA, Zarychanski R. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26;385(9):777-789. doi: 10.1056/NEJMoa2103417. PMID: 34551722 

ATTACC Investigators; ACTIV-4a Investigators; REMAP CAP Investigators; Lawler PR, Goligher EC, Berger JS, Neal MD, McVerry BJ, Nicolau JC, Gong MN, Carrier M, Rosenson RS, Reynolds HR, Turgeon AF, Escobedo J, Huang DT, Bradbury CA, Houston BL, Kornblith LZ, Kumar A, Kahn SR, Cushman M, McQuilten Z, Slutsky AS, Kim KS, Gordon AC, Kirwan BA, Brooks MM, Higgins AM, Lewis RJ, Lorenzi E, Berry SM, Berry LR, Aday AW, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Costantini TW, de Brouwer S, G Derde LP, Detry MA, Duggal A, Dzavik V, Effron MB, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, Fowler RA, Galanaud JP, Galen BT, Gandotra S, Garcia-Madrona S, Girard TD, Godoy LC, Goodman AL, Goossens H, Green C, Greenstein YY, Gross PL, Hamburg NM, Haniffa R, Hanna G, Hanna N, Hegde SM, Hendrickson CM, Hite RD, Hindenburg AA, Hope AA, Horowitz JM, Horvat CM, Hudock K, Hunt BJ, Husain M, Hyzy RC, Iyer AVN, Jacobson JR, Jayakumar D, Keller NM, Khan A, Kim Y, Kindzelski AL, King AJ, Knudson MM, Kornblith AE, Krishnan V, Kutcher ME, Laffan MA, Lamontagne F, Le Gal G, Leeper CM, Leifer ES, Lim G, Lima FG, Linstrum K, Litton E, Lopez-Sendon J, Lopez-Sendon Moreno JL, Lother SA, Malhotra S, Marcos M, Saud Marinez A, Marschall JC, Marten N, Matthay MA, McAuley DF, McDonald EG, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Moore SC, Morillo Guerrero RM, Mouncey PR, Murthy S, Nair GB, Nai R, Nichol AD, Nunez-Garcia B, Pandey A, Park PK, Parke RL, Parker JC, Parnia S, Paul JD, Perez Gonzalex YS, Pompilio M, Prekker ME, Quigley JG, Rost NS, Rowan K, Santos FO, Santos M, Santos MO, Satterwhite L, Saunders CT, G Schutgens RE, Seymour CW, Siegal DM, Silva Jr DG, Shankar-Hari M, Sheehan JP, Singhal AB, Solvason D, Stanworth SJ, Tritschler T, Turner AM, van Bentum-Puijk W, van de Veerdonk FL, van Diepen S, Vazquez-Grande G, Wahid L, Wareham V, Wells BJ, Widmer RJ, Wilson JG, Yuriditsky E, Zampieri FG, Angus DC, McArthur CJ, Webb SA, Farkouh ME, Hochman JS, Zarychanski R. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26;385(9):790-802. PMID: 34351721

Neven P, Rugo HS, Tolaney SM, Iwata H, Toi M, Goetz MP, Kaufman PA, Lu Y, Haddad N, Hurt KC, Sledge Jr GW. Abemaciclib plus fulvestrant in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in premenopausal women: subgroup analysis from the MONARCH 2 trial. Breast Cancer Res. 2021 Aug 23;23(1);87. doi: 10.1186/s13058-021-01463-2. PMID: 34425869

Gangaraju R, Koh I, Irvin MR, Lange L, Houghton DE, Herrera DA, Safford M, Cushman M, Bhatia S, Zakai NA. Peripheral blood cytopenia and risk of cardiovascular disease and mortality. J Am Heart Assoc 2021 Sep 21;10(18):e020809. doi: 10.1161/JAHA.121.020809. PMID: 34514816

Munger JA, Koh I, Howard G, Howard VJ, Plante TB, Wilkinson K, Cushman M, Zakai NA. Television viewing, physical activity and venous thromboembolism risk: the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study. J Thromb Haemost 2021 Sep;19(9):2199-2205. doi: 10.1111/jth.15408. PMID: 34077616

Alonso A, Norby FL, MacLehose RF, Zakai NA, Walker RF, Adam TJ, Lutsey PL. Claims-Based Score for the Prediction of Bleeding in a Contemporary Cohort of Patients Receiving Oral Anticoagulation for Venous Thromboembolism. J Am Heart Assoc. 2021 Sep 21;10(18):e021227. doi: 10.1161/JAHA.121.021227. PMID: 34514806

Connolly RM, Zhao F, Miller KD, Lee MJ, Piekarz RL, Smith KL, Brown-Glaberman UA, Winn JS, Faller BA, Onitilo AA, Burkard ME, Budd GT, Levine EG, Royce ME, Kaufman PA, Thomas A, Trepel JB, Wolff AC, Sparano JA. E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group. J Clin Oncol. 2021 Oct 1;39(28):3171-3181. doi: 10.1200/JCO.21.00944. PMID: 34357781

Patel J, Pallazola VA, Dudum R, Greenland P, McEvoy JW, Blumenthal RS, Virani SS, Miedema MD, Shea S, Yeboah J, Abbate A, Hundley WG, Karger AB, Tsai MY, Sathiyakumar V, Ogunmoroti O, Cushman M, Savji N, Liu K, Nasir K, Blaha MJ, Martin SS, Al Rifai M. Assessment of Coronary Artery Calcium Scoring to Guide Statin Therapy Allocation According to Risk-Enhancing Factors: The Multi-Ethnic Study of Atherosclerosis. JAMA Cardiol 2021 Oct 1;6(10):1161-1170. doi: 10.1001/jamacardio.2021.2321. PMID: 34259820

Sholzberg M, Tang GH, Rahhal H, AlHamzah M, Kreuziger LB, Áinle FN, Alomran F, Alayed K, Alsheef M, AlSumait F, Pompilio CE, Sperlich C, Tangri S, Tang T, Jaksa P, Suryanarayan D, Almarshoodi M, Castellucci LA, James PD, Lillicrap D, Carrier M, Beckett A, Colovos C, Jayakar J, Arsenault MP, Wu C, Doyon K, Andreou ER, Dounaevskaia V, Tseng EK, Lim G, Fralick M, Middeldorp S, Lee AYY, Zuo F, da Costa BR, Thorpe KE, Negri EM,  Cushman M, Jüni P; RAPID trial investigators. Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial. BMJ 2021 Oct 14;375:n2400. doi: 10.1136/bmj.n2400. PMID: 34649864

Shabani M, Bakhshi H, Ostovaneh MR, Ma X, Wu CO, Ambale-Venkatesh B, Blaha MJ, Allison MA, Budoff MJ, Cushman M, Tracy RP, Herrington DM, Szklo M, Cox C, Bluemke DA, Lima JAC. Temporal change in inflammatory biomarkers and risk of cardiovascular events: the Multi-ethnic Study of Atherosclerosis. ESC Heart Fail 2021 Oct;8(5):3769-3782. doi: 10.1002/ehf2.13445. PMID: 34240828

Lutsey PL, Walker RF, MacLehose RF, Norby FL, Evensen LH, Alonso A, Zakai NA. Inpatient Versus Outpatient Acute Venous Thromboembolism Management: Trends and Postacute Healthcare Utilization From 2011 to 2018. J Am Heart Assoc. 2021 Oct 19;10(20):e020428. doi: 10.1161/JAHA.120.020428. PMID: 34622678

Neven P, Johnston SR, Toi M, Sohn J, Inoue K, Pivot X, Burdaeva O, Okera M, Masuda N, Kaufman PA, Koh H, Grischke EM, Conte PF, Lu Y, Haddad N, Hurt KC, Llombart-Cussac A, Sledge GW. MONARCH 2: Subgroup Analysis of Patients Receiving Abemaciclib Plus Fulvestrant as First-Line and Second-Line Therapy for HR+, HER2-Advanced Breast Cancer. Clin Cancer Res. 2021 Nov 1;27(21):5801-5809. doi: 10.1158/1078-0432.CCR-20-4685. PMID: 34376533

Miller LM, Wu C, Hirsch CH, Lopez OL,  Cushman M, Odden MC. Cardiovascular damage phenotypes and all-cause and CVD mortality and older adults. Ann Epidemiol 2021 Nov;63:35-40. doi: 10.1016/j.annepidem.2021.07.012. PMID: 34339835

Aditi S, Adrianzen Herrera DA. Ruxolitinib in CMML: A Case Study of Innovative Trial Design in a Rare Cancer. Clin Cancer Res. 2021 Nov 15;27(22):6069-6071. doi: 10.1158/1078-0432.CCR-21-2578. PMID: 34531297

Folsom AR, deVries PS, Cushman M, No prospective association of a polygenic risk score for coronary artery disease with venous thromboembolism incidence. J Thromb Haemost 2021 Nov;19(11):2841-2844. doi: 10.1111/jth.15501. PMID: 34409733

Shukla GS, Pero SC, Mei L, Hitchcox S, Fung M, Sprague J, Krag DN. Preparation of clinical-grade WBCs using leukocyte reduction filters.  J Immunol Methods. 2021 Dec;499:113157. doi: 10.1016/j.jim.2021.113157. PMID: 34597620

Mattern L, Chen C, McClure LA, Brockman J, Cushman M, Judd S, Kahe K. Serum zinc levels and incidence of ischemic stroke: The Reasons for Geographic and Racial Differences in Stroke Study. Stroke 2021 Dec;52(12):3953-3960. doi: 10.1161/STROKEAHA.120.033187. PMID: 34412513

Talasaz AH, Sadeghipour P, Aghakouchakzadeh M, Kakavand H, Ariannejad H, Connors JM, Hunt BJ, Berger JS, Van Tassell BW, Middeldorp S, Piazza G, Weitz JI, Cushman M, Lip GYH, Goldhaber SZ, Bikdeli B. Use of novel antithrombotic agents for COVID-19: systemic summary of ongoing randomized controlled trials. J Thromb Haemost 2021 Dec;19(12):3080-3089. doi: 10.1111/jth.15533. PMID: 34538017

Couch CA, Gray MS, Shikany JM, Howard VJ, Howard G, Long DL, McClure LA, Manly JJ, Cushman M, Zakai NA, Pearson KE, Levitan EB, Judd SE. Correlates of a southern diet pattern in a national cohort study of blacks and whites: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study. Br J Nutrition 2021; Dec 28;126(12):1904-1910. PMID: 33632366

Levitan EB, Howard VJ, Cushman M, Judd SE, Tison SE, Yuan Y, Kamin Mukaz D, Wang HE,  Pamir N, Plante TB, Juraschek SP, Safford MM, Goyal P. Health care experiences during the COVID-19 pandemic by race and social determinants of health among adults age ≥58 years in the REGARDS Study. BMC Public Health 2021 Dec 11;21(1):2255. doi: 10.1186/s12889-021-12273-8. PMID: 34895192

Kamin Mukaz D, Gergi M, Koh I, Zakai NA, Judd SE, Sholzberg M, Baumann Kreuziger L, Freeman K, Colovos C, Olson NC, Cushman M. Thrombo-inflammatory biomarkers and D-dimer in a biracial cohort study. Res Pract Thromb Haemost. 2021 Dec 7;5(8):e12632. doi: 10.1002/rth2.12632. PMID: 34934895

Sholzberg M, da Costa BR, Tang GH, Rahhal H, AlHamzah M, Baumann Kreuziger L, Ní Áinle F, Almarshoodi MO, James PD, Lillicrap D, Carrier M, Beckett A, Fralick M, Middeldorp S, Lee AYY, Thorpe KE, Negri EM, Cushman M, Jüni P; RAPID Trial Investigators. Randomized trials of therapeutic heparin for COVID-19: A meta-analysis. Res Pract Thromb Haemost 2021 Dec 17;5(8):e12638. doi: 10.1002/rth2.12638 PMID: 34977448

Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP. Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. PMID: 34706549. 

Ruhl AP, Jeffries N, Yang Y, Naik RP, Patki A, Pecker LH, Mott BT,  Zakai NA, Winkler CA, Kopp JB, Lange LA, Irvin MR, Gutierrez OM, Cushman M, Ackerman HC. Alpha globin gene copy number is associated with prevalent chronic kidney disease and incident end-stage kidney disease among Black Americans. J Am Soc Nephrol 2022 Jan;33(1):213-224. doi: 10.1681/ASN.2021050653. PMID: 34706968

Berger JS, Kornblith LZ, Gong MN, Reynolds HR, Cushman M, Cheng Y, McVerry BJ, Kim KS, Lopes RD, Atassi B, Berry S, Bochicchio G, de Oliveira Antunes M, Farkouh ME, Greenstein Y, Hade EM, Hudock K, Hyzy R, Khatri P, Kindzelski A, Kirwan BA, Baumann Kreuziger L, Lawler PR, Leifer E, Lopez-Sendon Moreno J, Lopez-Sendon J, Luther JF, Nigro Maia L, Quigley J, Sherwin R, Wahid L, Wilson J, Hochman JS, Neal MD; ACTIV-4a Investigators. Effect of P2Y12 inhibitors on survival free of organ support among non-critically ill hospitalized patients with COVID-19: a randomized clinical trial. JAMA 2022 Jan 18;327(3):227-236. doi: 10.1001/jama.2021.23605. PMID: 35040887

Jaffray J, Kreuziger LB, Branchford B, Wee CP, Faustino EV, Zakai NA, Croteau SE, Silvey M, Fargo JH, Cooper JD, Bakeer N, Stillings A, Krava E, Young G, Goldenberg NA. Symptomatic pulmonary embolus after catheter removal in children with catheter related thrombosis: A report from the CHAT Consortium. J Thromb Haemost. 2022 Jan;20(1):133-137. doi: 10.1111/jth.15548. PMID: 34623749

Ades S, Herrera DA, Lahey T, Thomas AA, Jasra S, Barry M, Sprague J, Dittus K, Plante TB, Kelly J, Kaufman PA, Khan F, Hammond CJ, Gernander K, Parsons P, Holmes C. Cancer Care in the Wake of a Cyberattack: How to Prepare and What to Expect. JCO Oncol Pract. 2022 Jan;18(1):23-34. doi: 10.1200/OP.21.00116. PMID: 34339260

Jaffray J, Mahajerin A, Branchford B, Nguyen ATH, Faustino EV, Silvey M, Croteau SE, Fargo JH, Cooper JD, Bakeer N, Zakai NA, Stillings A, Krava E, Amankwah EK, Young G, Goldenberg NA. A New Risk Assessment Model for Hospital-Aquired Venous Thromboembolism in Critically Ill Children: A Report From the Children’s Hospital-Aquired Thrombosis Consortium. Pediatr Crit Care Med. 2022 Jan 1;23(1):e1-e9. doi: 10.1097/PCC.0000000000002826. PMID: 34406168

King JB, Pinheiro LC, Bryan Ringel J, Bress AP, Shimbo D, Muntner P, Reynolds K, Cushman M, Howard G, Manly JJ, Safford MM. Multiple social vulnerabilities to health disparities and hypertension and death in the REGARDS study. Hypertension 2022 Jan;79(1):196-206. doi: 10.1161/HYPERTENSIONAHA.120.15196 PMID: 34784734

Reading Turchioe M, Soliman EZ, Goyal P, Merkler AE, Kamel H, Cushman M, Soroka O, Masterson Creber R, Safford MM. Atrial fibrillation and stroke symptoms in the REGARDS study. J Am Heart Assoc 2022 Jan 18;11(2):e022921. doi: 10.1161/JAHA.121.022921. PMID: 35023350

Long DL, Guo B, McClure LA, Jaeger BC, Tison SE, Howard G, Judd SE, Howard VJ, Plante TB, Zakai NA, Koh I, Cheung KL, Cushman M. Biomarkers as MEDiators of racial disparities in Risk factors (BioMedioR): rationale, study design and statistical considerations. Ann Epidemiol 2022 Feb;66:13-19. doi: 10.1016/j.annepidem.2021.10.101. PMID: 34742867

Peper KM, Guo B, Long DL, Howard G, Carson AP, Howard VJ, Judd SE, Zakai NA, Cherrington A, Cushman M, Plante TB. C-reactive protein and racial differences in type 2 diabetes incidence: The REGARDS study. J Clin Endocrinol Metab. 2022 Feb 8;dgac074. doi: 10.1210/clinem/dgac074. PMID: 35137178

Thomas AA, Wright H, Chan K, Ross H, Prasad P, Goodwin A, Holmes CE. Safety of apixaban for venous thromboembolic primary prophylaxis in patients with newly diagnosed malignant glioma. J Thromb Thrombolysis. 2022 Feb;53(2):479-484. doi: 10.1007/s11239-021-02537-w. PMID: 34347201

Short S, Wilkinson K, Long DL, Kissela BM, Howard G, Judd SE, Schulte J, Cushman M. Pro-enkephalin A and ischemic stroke risk: the REasons for Geographic and Racial Differences in Stroke cohort. J Stroke Cerebrovasc Dis 2022 Feb;31(2):106237. doi: 10.1016/j.jstrokecerebrovasdis.2021.106237. PMID: 34896817

Long, DL, Guo, B, McClure, LA, Jaeger, BC, Tison, S, Howard, G, Judd, SE, Howard, VJ, Plante, TB,  Zakai, NA, Koh, I, Cheung, KL, Cushman, M. Biomarkers as MEDiators of racial disparities in Risk factors (BioMedioR): rationale, study design and statistical considerations. Ann Epidemiol 2022 Feb;66:13-19. doi: 10.1016/j.annepidem.2021.10.010. PMID: 34742867

Okado I, Pagano I, Cassel K, Su’esu’e A, Rhee J, Berenberg J, Holcombe RF. Clinical Research Professional Providing Care Coordination Support: A Study of Hawaii Minority/Underserved NCORP Community Site Trial Participants. JCO Oncol Pract. 2022 Mar 16;OP2100655. doi: 10.1200/OP.21.00655. PMID: 35294261

Wang H, Rosendaal FR, Cushman M, van Hylckama Vlieg A. Association between cardiovascular risk factors and venous thromboembolism in the elderly. Res Pract Thromb Haemost 2022 Mar 1;6(2):e12671. doi: 10.1002/rth2.12671. PMID: 35252737

Anker CJ, Lester-Coll NH, Akselrod D, Cataldo PA, Ades S. The Potential for Overtreatment With Total Neoadjuvant Therapy (TNT): Consider One Local Therapy Instead. Clin Colorectal Cancer. 2022 Mar;21(1):19-35. doi: 10.1016/j.clcc.2022.11.001. PMID: 35031237

Nicoli C, Long DL, Plante TB, Howard G, Judd SE, Schulte J, Cushman M. Pro-Neurotensin/Neuromedin N and Hypertension Risk: a Prospective Study. Am J Hypertension; 2022 Mar 8;35(3):281-288. doi: 10.1093/ajh/hpab166. PMID: 34655288

Wang H, Cushman M, Rosendaal FR, van Hylckama Vlieg A. Association of remote history of venous thrombosis with risk of venous thrombosis after age 70 years. JAMA Netw Open 2022 Mar 1;5(3):e224205. doi: 10.1001/jamanetworkopen.2022.4205. PMID: 35333359

Ponce SB,  Barry MM, Dizon DS, Katz MS, Murphy M, Teplinsky E, Tinianov S, Attai DJ, Markham MJ. Netiquette for social media engagement for oncology professionals. Future Oncol. 2022 Mar;18(9):1133-1141. doi: 10.2217/fon-2021-1366. PMID: 35109663

Jasra S, Giricz O, Zeig-Owens R, Pradhan K, Goldfarb DG, Barreto-Galvez A, Silver AJ, Chen J, Sahu S, Gordon-Mitchell S, Choudhary GS, Aluri S, Bhagat TD, Shastri A, Bejan CA, Stockton SS, Spaulding TP, Thiruthuvanathan V, Goto H, Gerhardt J, Haider SH, Veerappan A, Bartenstein M, Nwankwo G, Landgren O, Weiden MD, Lekostaj J, Bender R, Fletcher F, Greenberger L, Ebert BL, Steidl U, Will B, Nolan An, Madireddy A, Savona MR, Prezant DJ, Verma A. High Burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster. Nat Med. 2022 Mar;28(3):468-471. doi: 10.1038/s41591-022-01708-3. PMID: 35256801

Chidharla A, Utengen A, Attai DJ, Drake EK van Londen GJ, Subbiah IM, Henry E, Murphy M, Barry MM, Manochakian R, Moerdler S, Loeb S, Graff SL, Leyfman Y, Thompson MA, Markham JM. Social Media and Professional Development for Oncology Professionals. JCO Oncol Pract. 2022 Mar 21;OP2100761. doi: 10.1200/OP.21.00761. PMID: 35312343

Bruno XJ, Koh I, Lutsey PL, Walker RF, Roetker NS, Wilkinson K, Smith NL, Plante TB, Repp AB, Holmes CE, Cushman M, Zakai NA. Venous thrombosis risk during and after medical and surgical hospitalizations: The medical inpatient thrombosis and hemostasis (MITH) study. J Thromb Haemost. 2022 Apr 15. doi: 10.0000/jth.15729. PMID: 35426248

Ades S, Pulluri B, Holmes CE, Lal I, Kumar S, Littenberg B. Risk factors for venous thromboembolism in metastatic colorectal cancer with contemporary treatment: A SEER-Medicare analysis. Cancer Med. 2022 Apr;11(8):1817-1826. doi: 10.1002/cam4.4581. PMID: 35129311

Chaudhary NS, Tiwari HK, Hidalgo BA, Limdi NA, Reynolds RJ, Cushman M, Zakai NA, Lange L, Judd SE, Winkler CA, Kopp JB, Gutiérrez OM, Irvin MR. APOL1 Risk Variants Associated with Serum Albumin in a Population-Based Cohort Study. Am J Nephrol 2022;53(2-3):182-190. doi: 10.1159/000520997. PMID: 35100591

Gereg C, Conant JL, Jasra S, Devitt KA, Gardner JA. Acute Myeloid Leukemia with Myelodysplasia-Related Changes Presenting as Vitamin B12 Deficiency: A Cautionary Tale. J Assoc Genet Technol. 2021;47(4):218-223. PMID: 34897112

Cushman M. Are women equal? Considering impact of therapeutic abortion bans on science. Res Pract Thromb Haemost 2022;6:e12742.

Division of Immunobiology

Abbas Raza, Sean A. Diehl, Laure K. Case, Dimitry N. Krementsov, Dawei Li, Jason Kost, Robyn L. Ball, Elissa J. Chesler, Vivek M. Philip, Rui Huang, Yan Chen, Runlin Ma, Anna L. Tyler, J. Mathew Mahoney, Elizabeth P. Blankenhorn, Cory Teuscher. Genetic Analysis of Bphse: a Novel Gene Complementing Resistance to Bordetella pertussis-Induced Histamine Sensitization; bioRxiv 2021.08.18.456822; doi: https://doi.org/10.1101/2021.08.18.456822

Bruce EA, Mills MG, Sampoleo R, Perchetti GA, Huang M, Despres HW, Shirley D , Jerome KR, Greninger AL, Botten JW. Predicting Infectivity: Comparing Four PCR-based Assays to Detect Culturable SARS-CoV-2 in Clinical Samples. EMBO Molecular Medicine. 2022;14(2):e15290. Epub 2021/12/05. doi: 10.15252/emmm.202115290. PubMed PMID: 34862752; PMCID: PMC8819313.

Budd, R.C., Scharer, C.D., Barrantes-Reynolds, R., Legunn, S., and Fortner, K.A.  T cell homeostatic proliferation promotes a redox state that drives metabolic and epigenetic upregulation of inflammatory pathways in lupus.  Antioxidants and Redox Signaling. 36:410-422, 2021.

Drayman N, DeMarco JK, Jones KA, Azizi SA, Froggatt HM, Tan K, Maltseva NI, Chen S, Nicolaescu V, Dvorkin S, Furlong K, Kathayat RS, Firpo MR, Mastrodomenico V, Bruce EA, Schmidt MM, Jedrzejczak R, Muñoz-Alía MÁ, Schuster B, Nair V, Han KY, O'Brien A, Tomatsidou A, Meyer B, Vignuzzi M, Missiakas D, Botten JW, Brooke CB, Lee H, Baker SC, Mounce BC, Heaton NS, Severson WE, Palmer KE, Dickinson BC, Joachimiak A, Randall G, Tay S. Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.  Science. 2021 Aug 20;373(6557):931-936. doi: 10.1126/science.abg5827. Epub 2021 Jul 20. PMID: 34285133 

Inessa Manuelyan, Anna M. Schmoker, Boyd L. Yount Jr, Philip Eisenhauer, Judith I. Keller, Clarissa Gold, Dante Terino, Christopher M. Ziegler, Jeff Alexander, Heather Driscoll, Edward Hutchinson, David Bhella, Christopher D. Syme, Douglas G. Widman, Mark T. Heise, Ralph S. Baric, Bryan A. Ballif,  Jason W. Botten. A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding. bioRxiv https://doi.org/10.1101/2021.11.24.469793. November 25, 2021

Joseph Findley, Elizabeth McGee, Chin-Yo Lin, Dimitry Krementsov, Cory Teuscher.  Coro2a, An Expression Quantitative Trait Gene Underlying Estq1, Controls Uterine Responsiveness to Estradiol; bioRxiv 2021.02.28.433254; doi: https://doi.org/10.1101/2021.02.28.433254

Li J, Ma Y, Paquette JK, Richards AC, Mulvey MA, Zachary JF, Teuscher C, Weis JJ.  The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis. PLoS Pathog. 2022 Mar 24;18(3):e1010365. doi: 10.1371/journal.ppat.1010365. eCollection 2022 Mar.PMID: 35324997

Mills MG, Bruce E, Huang ML, Crothers JW, Hyrien O, Oura CAL, Blake L, Jordan AB, Hester S, Wehmas L, Mari B, Barby P, Lacoux C, Fassy J, Vial P, Vial C, Martinez JRW, Oladipo OO, Inuwa B, Shittu I, Meseko CA, Chammas R, Santos CF, Jose Dionisio T, Garbieri TF, Parisi VA, Mendes-Correa MC, dePaula AV, Romano CM, Goes LGB, Minoprio P, Campos AC, Cunha MP, Vilela APP, Nyirenda T, Mkakosya RS, Muula AS, Dumm RE, Harris RM, Mitchell CA, Pettit S†, Botten J†, Jerome KR†. An international, interlaboratory ring trial confirms the feasibility of an open-source, extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples. PLoS One. 2022;17(1):e0261853. Epub 2022/01/14. doi: 10.1371/journal.pone.0261853. PubMed PMID: 35025926; PMCID: PMC8758094.

Montgomery TL, Paavola M, Bruce EA, Botten JW, Crothers JW, Krementsov DN.  Laboratory Worker Self-Contamination with Noninfectious SARS-CoV-2 DNA Can Result in False-Positive Reverse Transcriptase PCR-Based Surveillance Testing.  J Clin Microbiol. 2021 Jun 18;59(7):e0072321. doi: 10.1128/JCM.00723-21. Epub 2021 Jun 18. PMID: 33952597 

Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ. Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.  mBio. 2021 Aug 31;12(4):e0253120. doi: 10.1128/mBio.02531-20. Epub 2021 Jul 6. PMID: 34225492 

L. Shrestha, M.J. Lin, H. Xie, M.G. Mills, A. Shaw, M. Bakhash, V.P. Gaur, R. J. Livingston, J. Castor, E.A. Bruce, J.W. Botten, ML. Huang, K.R. Jerome, A.L. Greninger,P. Roychoudhury. Clinical performance characteristics of the Swift Normalase Amplicon Panel for sensitive recovery of SARS-CoV-2 genomes. medRxiv. https://doi.org/10.1101/2021.10.22.21265255. October, 2021

Thoms, BL, Gosselin, J, Libman, B, Littenburg, and Budd, RC.  Efficacy of combination therapy with the JAK inhibitor baricitinib in the treatment of COVID-19. SN Comprehensive Clinical Medicine. 4:42-55, 2022. https://doi.org/10.1007/s42399-022-01121-4.

Victor J, Deutsch J, Whitaker A, Lamkin EN, March A, Zhou P, Botten JW, Chatterjee N.  SARS-CoV-2 triggers DNA damage response in Vero E6 cells. Biochem Biophys Res Commun. 2021 Nov 19;579:141-145. doi: 10.1016/j.bbrc.2021.09.024. Epub 2021 Sep 15. PMID: 34600299 

Division of Infectious Disease

Feinberg N, Campbell B, Bazylewicz M, Brown WD, Singh D, Whitman T, Alston WK, Ulano A, Sawatzky B, Hale AJ. Brain Abscess with pyogenic ventriculitis. IDCases  2022  Apr 12:28:e01503.  Doi:   10.1016/j.idcr.2022 e01503.  eCollection PMID   35469210

He YT, Peterson K, Crothers J, Dejace  J, Hale AJ. Endocarditis and systemic embolization from Whipple’s disease. ID Cases   2021 Mar 31:24:e01105  doi:  10.1016/j.idcr.2021 e01105   eCollection 2021. PMID   33868927

Ricottta DN, Hale AJ, Freed JA, Scribner TE, Zeidel ML, Herzig SJ. Generalists as Clinical Physiologist: Bringing Science Back to the Beside. J Gen Intern Med. 2021 Dec; 36(12):3847-3851.  Doi:  10.1007/s11606-021-06978-0  Epub 2021 July 8. PMID   34240283

Hale T, Angrist N, Hale AJ, Kira B, Majumdar S, Petherick A, Phillips T, Sridhar D, Thompson RN, Webster S, Zhang Y. Government responses and COVID-19 deaths:  Global evidence across multiple pandemic waves. PLoS One. 2021  July 9; 16(7): e0253116.  Doi:  10.1371/journal.pone.0253116.  eCollection 2021
PMID   34242239

Bougioukas L, Campbell B, Crooker K, Freed JA, Wilcock J, Singh D,  Hale AJ. Invasive Aspergillus flavus sinusitis in an immunocompetent patient using intranasal cocaine. ID Cases. 2021  Nov 2:26e01327.  Doi:  10.1016/j.idcr.2021  .e01327   eCollection 2021. PMID 34904802

Ricotta DN, Freed JA,   Hale AJ, Trgen E, Smith CC, Huang GC. A Resident-as-Leader Curriculum for Managing Inpatient Teams. Teach Learn Med.  2022 Jan 13:1-10.  Doi:  10.1080 / 10401334.2021.2009347  Online ahead of print. PMID 35023796

Hale AJ, Mathur S, Dejace  J, Lidofsky SD. Statewide Assessment of the Hepatitis C Virus Care Cascade for incarcerated Persons in Vermont. Public Health Rep. 2022  Mar 9:333549221077070.  Doi: 10.1177/00333549221077070. Online ahead of print. PMID: 35264027

Huston CD. The Clofazimine for Treatment of Cryptotsporidiosis in HIV –Infected adults (CRYPTOFAZ) and lessons learned  for Anticryptosporidial Drug Development. Clin Inf Dis 2021 Jul  15:73(2):192-194.  Doi:  10.1093 / cid/ ciaa425 PMID 32277815

OBoh E, Schubert TJ, Teixeira JE, Stebbins EE, Miller P, Philo E, Thakellapallil H, Campell SD, Griggs DW, Huston CD, Meyer MJ. Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin. J Med Chem. 2021 Aug 12:64(15): 11729-11745.Doi: 10.1021 /acs.jmedchem. 1c01136.  Epub 2021 Aug 3. PMID  34342443

Falsey AR, Sobieszczyk ME,…… Kirkpatrick BD,    Astra Zeneca AZD1222 clinical Study Group. Phase 3 Safety and Efficacy of AZD1222 ( ChAdOx1 nCoV-19)  Covid-19 Vaccine. N Engl J Med. 2021 Dec  16;385 (25): 2348-2360. Doi:  10.1056/NEJMoa2105290. Epub 2021 Sept 29. PMID 34587382

Bullis SSM, Grebber B, Cook S, Graham NR, Carmolli M, Dickson D   Diehl SA, Kirkpatrick BD, Lee B. SARS CoV-2 seroprevalence in a US school district during Covid-19. BMJ Paediatr Open.  2021 Oct 27;5(1) : e001259. Doi: 10.1136/bmjpo-2021-001259. eCollection 2021. PMID 34725646

Leslie JL, Weddle E, Yum Lk, Lin Y, Jenior ML, Lee B, Ma JZ, Kirkpatrick BD, Nayak U, Platts-Mills JA, Agaisse HF, Haque R, Petri WA. Lewis Blood-group Antigens Are Associated with Altered Susceptibility to Shigellosis. Clin Infect Dis. 2021 Jun 1; 72(11):e868-e871.  Doi: 10.1093/CID/ ciaa 1409. PMID   32940644

Robertson RC, Church JA, Edens TJ, Mutasa K, Min Geum H, Baharmand I, Gill SK…Kirkpatrick BD…..SHRINE  Trial Team. The Fecal microbiome and rotavirus vaccine immunogenicity in rural Zimbabwean infants, Vaccine 2021 Sept 7;39(38): 5391-5400   doi:  10.1016/j.vaccine.2021.07.076  Epub 2021  Aug 13. PMID 34393020

Williams FB, Kader A, Colgate ER, Dickson DM, Carmolli M,  Udden MI……..Kirkpatrick BD. Maternal Secretor Status Affects Oral Rotavirus Vaccine Response in Breastfed infants in Bangladesh. J Infec Dis. 2021 Oct 13;224(7) : 1147-1151.  Doi: 10.1093/infdis/jiaa101. PMID 32157282

Church JA, Rukobo S, Govha M, Gough EK, Chasekwa B, Lee B, Carmolli MP, Panic G, Giallourou N, Ntozoni R ……Kirkpatrick BD. Associations between biomarkers of environmental enteric dysfunction and oral rotavirus vaccine immunogenicity in rural Zimbabwean infants. EClinical Medicine. 2021 Nov 15:41: 101173. Doi:  10.1016/j.eclinm.2021.101173 eCollection 2021 Nov. 
PMID 34825149

Stein CM, Benchk,P, …….Lahey T.  Methylome-wide Analysis Reveals Epigenetic marks Associate with Resistance to Tuberculosis in Human Immunodeficince Virus-infected individuals from East Africa. J Infect Dis  2021  Aug 16;224(4) : 695-704. Doi: 10.1093 / infdis/jiaa785. PMID 33400784

Ahern JW, Noyes CD, Smith LM, Alston WK. Twenty years of infection prevention: A longitudinal perspective from an academic medical center. Infect Contro Hosp Epidemiol. 2022 Jan ;43(1) : 115-117.  Doi: 10.1017/ ice.2021.312 Epub 2021 Aug 5. PMID  34350822

Smith LM,  Ahern JW. Antimicrobial Stewardship during a cyberattack. Infect Control Hosp Epidemiol. 2021 June 9:1 doi 10.1017/ice. 2021.235 Online Ahead of print. PMID 34102110

Husnik MJ, Brown ER, Dadabhi SS…….Singh D    MTN -020/Aspire Study Team. Correlates of Adherence of the Dapivirine Vaginal Ring for HIV -1 prevention. AIDS Behav 2021 Sept ;25(9): 2801-2814   doi: 10.1007/ s10461-021-03231-x. Epub 2021 June 11. PMID 34117592

Jessica W Crothers, Elizabeth Ross Colgate, Kelly J Cowan, Dorothy M Dickson, MaryClaire Walsh, Marya Carmoll, Peter F Wright, Elizabeth B Norton, Beth D Kirkpatrick.  Fractional-dose inactivated polio vaccine (fIPV) adjuvanted with double mutant Enterotoxigenic Escherichia coli heat labile toxin (dmLT) is well-tolerated and augments a systemic immune response to all three poliovirus serotypes in a randomized placebo-controlled trial. Vaccine. 2022 Apr 26;40(19):2705-2713. doi: 10.1016/j.vaccine.2022.03.056. Epub 2022 Mar 30. PMID   35367069

Katherine Peterson, Bradley Tompkins, John Ahern, Lindsay M Smith. The impact of a best practice Advisory on inpatient prescribing of piperacillin-tazobactum. Antimicrobial Stewardship  & healthcare epidemiology (2022) 2, e36, 1-2   Doi: 10.1017/ash2022.12. PMID  

Cindy D. Noyes,  Monica Raymond, Cristina Wojewoda, W. Kemper Alston. Impact of SARS-CoV-2 Vaccination on the incidence of COVID-10 among Healthcare Workers at an Academic Medical Center in Vermont. Antimicrobial Stewardship &Healthcare epidemiology (2022) DOI:  10.1017/ash.2022.15. PMID   

Division of Nephrology

Carver JA, Cheung KL. Feasibility and Acceptability of a Yogic Breathing/Mindfulness Meditation e-Intervention on Symptoms and COVID-19-Associated Anxiety in Patients Receiving Dialysis. J Palliat Med. 2021 Aug;24(8):1124-1125. doi: 10.1089/jpm.2021.0161. Epub 2021 Apr 5. PMID: 34152865.

Onuigbo MAC. Stopping RAS Inhibitors in Advanced CKD Chronic Kidney Disease and Cardiorenal Outcomes - Several Unanswered Questions Remain. Am J Med. 2021 May 4:S0002-9343(21)00273-4. doi: 10.1016/j.amjmed.2021.03.031. Epub ahead of print. PMID: 33961836.

Onuigbo, M.A.C. Postoperative Acute Kidney Injury in Abdominal Operations: a Critical Appraisal. Indian J Surg (2021). https://doi.org/10.1007/s12262-021-03031-6.

Hadjianastassiou VG, Soloukides A, Prikis M. The Emergence and Development of Solid Organ Transplantation in the Republic of Cyprus. Transplantation. 2021 Feb 1;105(2):267-270. doi: 10.1097/TP.0000000000003386. PMID: 33492110.

Onuigbo MA, Izuora A. The Impact of Elective Withdrawal of Long-Term Renin Angiotensin Aldosterone System Blockade in Chronic Kidney Disease Patients with Progressive Acute Kidney Injury: A Prospective 40-Months’ Single-Unit Cohort Study. Medical Research Archives, [S.l.], v. 9, n. 9, sep. 2021. ISSN 2375-1924. Available at: <https://www.esmed.org/MRA/mra/article/view/2549>. Date accessed: 10 may 2022. doi: https://doi.org/10.18103/mra.v9i9.2549. 

Kumar A, Bonnell LN, Prikis M, Solomon R. Impact of age mismatch between donor and recipient on heart transplant mortality. Clin Transplant. 2021 Mar;35(3):e14194. doi: 10.1111/ctr.14194. Epub 2020 Dec 29. PMID: 33336373.

Onuigbo MA, Ross A. Pseudohyperkalemia and the Need for Imperative Caution With the Newly Introduced Potent Potassium Binders: Two Cases. Cureus. 2021 Aug 14;13(8):e17179. doi: 10.7759/cureus.17179. PMID: 34548981; PMCID: PMC8437584.

Long DL, Guo B, McClure LA, Jaeger BC, Tison SE, Howard G, Judd SE, Howard VJ, Plante TB, Zakai NA, Koh I, Cheung KL, Cushman M. Biomarkers as MEDiators of racial disparities in risk factors (BioMedioR): Rationale, study design, and statistical considerations. Ann Epidemiol. 2022 Feb;66:13-19. doi: 10.1016/j.annepidem.2021.10.010. Epub 2021 Nov 3. PMID: 34742867; PMCID: PMC8920757.

Onuigbo MAC, Libman B, Lazarovich M. Benralizumab substitution monotherapy in symptomatic relapsing asthma dominant eosinophilic granulomatosis with polyangiitis. Immunopathol Persa. 2022;x(x):e0x. DOI:10.34172/ipp.2022. xx.

Hood VL. Sternberg K, DeWaal D, Asplin J, Mulligan C, Callas P. Association of Urine Findings with Metabolic Syndrome Traits in a Population of Patients with Nephrolithiasis. Kidney 360, 3:317-324, 2022

Onuigbo MA. COVID-19 infection recurrence in ESRD. Indian J Nephrol 2022;32:184-5

Cheung KL, Smoger S, Tamura MK, Stapleton RD, Rabinowitz T, LaMantia MA, Gramling R. Content of Tele-Palliative Care Consultations with Patients Receiving Dialysis. J Palliat Med. 2022 Mar 4. doi: 10.1089/jpm.2021.0539. Epub ahead of print. PMID: 35254866.

Bahadoram M, Labaykee S, Lakkakula BVKS, Keikhaei B, Nekouei Shahraki M, Mohammadi Jouabadi S, Onuigbo M, Ahmadizar S, Mahmoudian-Sani MR, Peymani P. World Kidney Day 2021 with the theme of living well with kidney disease; a review of current concepts. J Prev Epidemiol. 2021;6(1):e08. doi: 10.34172/ jpe.2021.08.

Onuigbo Macaulay. Mask Up America!!! - Stop This Deceptive Self-Destructive COVID-19 CHARADE!!!: The rantings of a perplexed US Nephrologist!!!. Authorea. March 30, 2022. DOI: 10.22541/au.164864293.36799088/v1. 

Stapleton RD*, Ford DW*, Sterba KR, Nadig NR, Ades S, Back AL, Carson SS, Cheung KL, Ely J, Kross EK, Macauley RC, Maguire JM, Marcy TW, McEntee JJ, Menon PR, Overstreet A, Ritchie CS, Wendlandt , Ardren SS, Balassone M, Burns S, Choudhury S, Diehl S, McCown E, Nielsen EL, Paul SR, Rice C, Taylor KK, Engelberg RA.  Evolution of Investigating Informed Assent Discussions about CPR in Seriously Ill Patients.  J Pain Symptom Manage 2022.  In press. (*equal contribution).

Prikis M, Cameron Alexandra. Paxlovid (Nirmatelvir/Ritonavir) and Tacrolimus Drug-Drug Interaction in a Kidney Transplant Patient with SARS-2-CoV infection. A Case Report. May 2022 In press. Transplantation Proceedings.

ABSTRACTS:

Macaulay Onuigbo, Kolade Olabode, Mohan Sengodan, MO170. “SWEET HYPOXIA” WITH ACUTE KIDNEY INJURY: THE UNPREDICTABILITY OF ACUTE HYPOXIC RESPIRATORY FAILURE IN COVID-19 INFECTION - A COMMUNITY HOSPITAL EXPERIENCE, Nephrology Dialysis Transplantation, Volume 36, Issue Supplement_1, May 2021, gfab092.0048, https://doi.org/10.1093/ndt/gfab092.0048

Macaulay Onuigbo, Sarah Sherman, Heng Tan, MO218. ALTERNATING EPISODES OF TRUE HYPERKALEMIA AND PSEUDOHYPERKALEMIA IN ADULT SICKLE CELL DISEASE - A NEPHROLOGIST'S DILEMA, Nephrology Dialysis Transplantation, Volume 36, Issue Supplement_1, May 2021, gfab092.0096, https://doi.org/10.1093/ndt/gfab092.0096

Onuigbo MA, Tan H, Sherman SE. Alternating Episodes of True Hyperkalaemia and Pseudohyperkalaemia in Adult Sickle Cell Disease: A Nephrologist's Dilemma. EMJ Nephrol. 2021;9[1]:55-57. Abstract Review No. AR6.

Onuigbo MA, Olabode K, Sengodan M. ‘Sweet Hypoxia’ with Acute Kidney Injury: The Unpredictability of Acute Hypoxic Respiratory Failure in COVID-19 Infection – a Community Hospital Experience. EMJ Nephrol. 2021;9[1]:48-49. Abstract Review No: AR2.

Onuigbo, M. POS-647 COMBINED HOME-HEMODIALYSIS PLUS IN-CENTER HEMODIALYSIS HYBRID REGIMEN AS A FAMILY-FRIENDLY WORK-FRIENDLY OPTION - THE FIRST OF ITS KIND. Kidney International Reports, Volume 7, Issue 2, S277

Onuigbo, M. POS-143 BENRAZILUMAB SUBSTITUTION MONOTHERAPY IS EFFECTIVE IN SYMPTOMATIC ASTHMA EXACERBATIONS OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS. Kidney International Reports, Volume 7, Issue 2, S61

Onuigbo, M. POS-094 PSEUDOHYPERKALEMIA AND THE NEWLY INTRODUCED POTENT POTASSIUM BINDERS: A CALL FOR IMPERATIVE CAUTION – TWO CASE SERIES. Kidney International Reports, Volume 7, Issue 2, S40

Onuigbo, M. POS-040 RENAL OUTCOMES FOLLOWING ELECTIVE WITHDRAWAL OF LONG-TERM STABLE RAAS-BLOCKADE IN CHRONIC KIDNEY DISEASE PATIENTS PRESENTING WITH PROGRESSIVE ACUTE KIDNEY INJURY. Kidney International Reports, Volume 7, Issue 2, S16 - S17

Onuigbo M, de Waal D. Family-Friendly & Work-Friendly Hybrid Hemodialysis: Combination Home Hemodialysis and In-Center Hemodialysis Regimen. Poster presented at the National Kidney Foundation Spring Meeting, April 2022, Boston, MA.

Division of Pulmonary Disease and Critical Care Medicine

Dixon AE, and Que LG. Obesity and Asthma. Seminars in Respiratory and Critical Care Medicine. 2022;in press.

Johnson O, Gerald LB, Harvey J, Roy G, Hazucha H, Large C, Burke A, McCormack M, Wise RA, Holbrook JT,  Dixon AE. An Online Weight Loss Intervention for People With Obesity and Poorly Controlled Asthma. J Allergy Clin Immunol Pract. 2022 Jun;10(6):1577-1586.e3. doi: 10.1016/j.jaip.2022.02.040. Epub 2022 Mar 15. PMID: 35304842; PMCID: PMC9188993.

Dixon AE, and Que LG. Obesity and Asthma. Semin Respir Crit Care Med. 2022.

Geng B, Dixon AE, Ko J, Janampally P, Haselkorn T, Holweg CTJ, et al. Impact of body mass index on omalizumab response in adults with moderate-to-severe allergic asthma. Ann Allergy Asthma Immunol. 2022;128(5):553-60.

Bhatawadekar SA, Peters U, Walsh RR, Daphtary N, MacLean ES, Hodgdon K, Kinsey CM, Kaminsky DA, Bates JHT, Dixon AE. Air Trapping versus Atelectasis in Obesity: Relationship to Late-Onset Nonallergic Asthma and Aging. Ann Am Thorac Soc. 2022 Jan;19(1):135-139. doi: 10.1513/AnnalsATS.202010-1317RL. PMID: 34343031; PMCID: PMC8787791.

Morris CR, Habibovic A, Dustin CM, Schiffers C, Lin MC, Ather JL, et al. Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease. Mucosal Immunol. 2022.

Mank MM, Reed LF, Walton CJ, Barup MLT, Ather JL, and Poynter ME. Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma. Am J Physiol Lung Cell Mol Physiol. 2022;322(2):L243-L57.

Kaminsky DA, Simpson SJ, Berger KI, Calverley P, de Melo PL, Dandurand R, et al. Clinical significance and applications of oscillometry. Eur Respir Rev. 2022;31(163).

Oliver AC, DeSarno M, Irvin CG, Kaminsky D, Tidey JW, Sigmon SC, et al. Effects of Reduced Nicotine Content Cigarettes on Fractional Exhaled Nitric Oxide and Self-Reported Respiratory Health Outcomes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage. Nicotine Tob Res. 2022;24(1):135-40.

Wise RA, Holbrook JT, Brown RH, Criner GJ, Dransfield MT, He J, et al. Clinical Trial of Losartan for Pulmonary Emphysema: Pulmonary Trials Cooperative LEEP Trial. American journal of respiratory and critical care medicine. 2022.

Kaminsky DA. Is There a Role for Using Race-Specific Reference Equations? Yes and No. American journal of respiratory and critical care medicine. 2022;205(7):746-8.

Bhakta NR, Kaminsky DA, Bime C, Thakur N, Hall GL, McCormack MC, et al. Addressing Race in Pulmonary Function Testing by Aligning Intent and Evidence With Practice and Perception. Chest. 2022;161(1):288-97.

Lehrer PM, Irvin CG, Lu SE, and Wamboldt FS. Relationships among pulmonary function, anxiety and depression in mild asthma: An exploratory study. Biol Psychol. 2022;168:108244.

Rossman MJ, Petrics G, Klansky A, Craig K, Irvin CG, and Haverkamp HC. Exercise-induced Bronchodilation Equalizes Exercise Ventilatory Mechanics despite Variable Baseline Airway Function in Asthma. Med Sci Sports Exerc. 2022;54(2):258-66.

Division of Rheumatology and Clinical Immunology

Budd, R.C., Scharer, C.D., Barrantes-Reynolds, R., Legunn, S., and Fortner, K.A.  T cell homeostatic proliferation promotes a redox state that drives metabolic and epigenetic upregulation of inflammatory pathways in lupus.  Antioxidants and Redox Signaling. 36:410-422, 2021.

Thoms BL, Gosselin J, Libman B, Littenberg B, Budd RC. Efficacy of Combination Therapy with the JAK Inhibitor Baricitinib in the Treatment of COVID-19. SN Compr Clin Med. 2022;4(1):42. doi: 10.1007/s42399-022-01121-4. Epub 2022 Jan 21. PMID: 35079694; PMCID: PMC8776555.

Onuigbo M, Libman B, Lazarovich M.  Benralizumab substitution monotherapy in symptomatic relapsing asthma-dominant eosinophilic granulomatosis with polyangiitis.  Immunopathologia Persa     Feb 2022

Maneval J, Bryant B, Ulano A, Waheed W, Nevares A. Isolated Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Hypertrophic Pachymeningitis. J Clin Rheumatol. 2022 Apr 1;28(3):e672-e674. doi: 10.1097/RHU.0000000000001845. PMID: 35325906.

Quality Program

Cardiovascular Medicine

Infeld M, Nicoli CD, Meagher S, Tompkins BJ, Wayne S, Irvine B, Betageri O, Habel N, Till S, Lobel J, Meyer M, Lustgarten DL. Clinical impact of Bachmann's bundle pacing defined by electrocardiographic criteria on atrial arrhythmia outcomes. Europace. 2022 Mar 19:euac029. doi: 10.1093/europace/euac029. Epub ahead of print. PMID: 35304608.  

Endocrinology

Barrett KV, Kennedy AG, Repp AB, Tompkins BJ, Gilbert MP. Predictors and Consequences of Inappropriate Thyroid Ultrasound in Hypothyroidism. Cureus 13(8): e17304. doi:10.7759/cureus.17304

Steinmetz-Wood SN, Kennedy AG, Tompkins BJ, Gilbert MP. Navigating the Debate on Managing Large (≥4cm) Thyroid Nodules. Int J Endocrinol. 2022 Apr 16;2022:6246150. https://doi.org/10.1155/2022/6246150. PMID: 35469125

Gilbert MP, DeVoe SG, Kennedy AG, Ogelby M, Consigli AB, Zimakas PJ, Repp AB, Robinson KJ. Improving the quality of health care transitions for young adults at an adult endocrinology clinic [abstract]. Diabetes. 2021 Jun;70(suppl 1):852-P. doi: 10.2337/db21-852-P.

Shah A, Gilbert M, Barrett K, Tompkins B, Kennedy AG. Inappropriate Use of Thyroid Uptake and Scan in Adult Patients with Suspected Graves' Disease. Poster presented virtually at: 90th Annual Meeting of the American Thyroid Association, September 30, 2021.

General Internal Medicine

Wahlberg KJ, Pay TD, Repp AB, Wahlberg EA, Kennedy AG. Effect of a Patient Safety Curriculum for Internal Medicine Residents on a Health Care System. ATS Scholar.12/15/21.doi: 10.34197/ats-scholar.2021-0088IN

Roberts S, Tompkins BJ, Kennedy AG. The effect of an educational intervention on primary care providers' knowledge, confidence, and frequency of patient counseling on strength training and bone density. Musculoskeletal Care. 2021 Dec 13. doi: 10.1002/msc.1611. Online ahead of print. PMID: 34897943 

Hospital Medicine

Bolton K, Lawler M, Hauptman J, Madden M, DeVoe SG, Kennedy AG, Tompkins BJ, Hodde NM. Patient experience on a hospital oncology service before and after implementation of a no-visitor policy during Covid-19. J Patient Exp. 2021 Jul 28;8:23743735211034620. doi: 10.1177/23743735211034620. PMID: 34377777.

Gau J, Nwora C, Eldakar-Hein ST,  Goel MS, Lahey T, Repp AB. Things We Do for No Reason™: Routine inclusion of race in the history of present illness. J Hosp Med. 2022; 17: 123-126. doi:10.12788/jhm.3650

Carey ME, Gilmore BL, Lawler MJ, Hoddwells M, Hale AJ, Repp AB. High value care in undergraduate medical education: Student & faculty perceptions of Choosing Wisely in the pre-clinical curriculum. Preventing Overdiagnosis Conference, Calgary, Alberta, Canada, June 2022.

Kennedy AG, Regier L. The Connected Team: Building Morale and Support. Workshop presented at the National Resource Center for Academic Detailing (NaRCAD) 9th International (Virtual) Conference on Academic Detailing, November 2021.

Pulmonary & Critical Care

Teneback CC, Prior C, Sender A, McCuin T, Weintraub Z, Brady CM, Ludlow M, Steiert K, Antell M, Huguenin B, DeVoe SG. 69: Implementation of a multifaceted mental health screening approach in an adult cystic fibrosis clinic. Journal of Cystic Fibrosis. November 2021. doi: 10.1016/S1569-1993(21)01494-6

Quality Program

Nenninger A, Ball SJ, Kennedy AG, Regier LD. "You're on Mute" - Lessons Learned with Virtual Academic Detailing. J Am Pharm Assoc (2003). 2022 Feb 11:S1544-3191(22)00055-3. doi: 10.1016/j.japh.2022.02.002. PMID: 35246402

Presentations