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A bridge from
Science to
Patient Care.
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Charles G. Irvin, Ph.D. |
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Contact Information
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Main Numbers:
Patient Information: (802) 847-1158
Research Lab: (802) 656-8928
Clinical Research Center: (802) 847-2193
Charles Irvin, Ph.D.
Director, Vermont Lung Center
Room 226, HSRF
University of Vermont, College of Medicine
149 Beaumont Ave.
Burlington, VT. 05405
Voice: (802) 656-8928
Fax: (802) 656-8926
Email:Charles.Irvin@uvm.edu
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Training and Professional Experience
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- B.A. (1972) Biology; Carroll College, Waukesha, WI.
- Ph.D. (1978) Pulmonary Physiology; Univ. of Wisconsin, Madison WI.
- Post-doc. (1978-1980) Lung Mechanics; McGill Univ. Montreal, Quebec, Canada.
- Assistant Professor (1980-1988); Dept of Medicine, National Jewish Center/University of Colorado, Denver, CO.
- Associate Professor (1988-1995); Dept of Medicine, National Jewish Center/University of Colorado, Denver, CO.
- Professor (1995-1998); Dept of Medicine, National Jewish Center/University of Colorado, Denver, CO.
- Professor (1998-Present), Dept. of Molecular Physiology & Biophysics, Dept. of Medicine, University of Vermont.
- Director (1998-Present), Vermont Lung Center, College of Medicine University of Vermont.
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Research Interests
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My main research interests focus on lung mechanics and the pathogenesis of asthma entailing both basic and clinical science.
- Asthma
- Lung Mechanics
- Airways Epithelium
- Airway Remodeling
- Sinusitis / Rhinitus
- Eosinophils
- Cationic Protein
- Clinical Trials
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Selected Publications
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- Effects of cool, dry air stimulation on peripheral lung mechanics in asthma. (Am J Respir Crit Care Med 2000 Jul;162(1):179-86)
- Airway-parenchyma uncoupling in nocturnal asthma. (Am J Respir Crit Care Med 2000 Jan;161(1):50-6)
- Distal lung dysfunction at night in nocturnal asthma. (Am J Respir Crit Care Med 2001 Jun;163(7):1551-6)
- New insights from lung function. (Curr Opin Allergy Clin Immunol 2001 Jun;1(3):205-9)
- The safety of inactivated influenza vaccine in adults and children with asthma. (N Engl J Med 2001 Nov 22;345(21):1529-36)
- Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations. (J Appl Physiol 2002 Jul;93(1):263-70)
- Unrestrained plethysmography is an unreliable measure of airway responsiveness in BALB/c and C57BL/6 mice.
- Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness.
- NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness.
- Defining a link with asthma in mice congenitally deficient in eosinophils.
- Early intervention of therapy in asthma.
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