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Northern New England Clinical and Translational Research (NNE-CTR) successes, events and news.


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Funding Opp: Genetics & Phenotypes Associated with Drug Abuse

January 2, 2019 by Jennifer Smith

The goals of this initiative are to discover allelic variants, genomic alterations, and functional changes associated with addictive behaviors in non-human animals through systems studies that employ genetic and genomics strategies. We also encourage applications that take genetic and/or genomics approaches to integrate data, delineate gene networks, and uncover the function of known or newly discovered genetic or epigenetic variants.

I would like to make you aware of a funding opportunity announcement, PAR-18-789 Genetic analysis of non-human animal models to understand the genomic architecture of substance use disorders and addictive behaviors <https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_pa-2Dfiles_PAR-2D18-2D789.html&d=DwMFAg&c=ST5Jxgx_zZ9nYuPWkSm01Luus8kzn0TCuX9tmQgnWms&r=AP2rDwfXnLanmfgmid0oPg&m=U-SsUu0R7wOxR8dXF_1DLF-7eazb5uQbkZqbjMHh3rA&s=ei6yYVaBQ4oe6DIf-2QPMM8Z3AZXAQA1fgz2mYTAJns&e=>.  The goals of this initiative are to discover allelic variants, genomic alterations, and functional changes associated with addictive behaviors in non-human animals through systems studies that employ genetic and genomics strategies. We also encourage applications that take genetic and/or genomics approaches to integrate data, delineate gene networks, and uncover the function of known or newly discovered genetic or epigenetic variants.

Investigators examining the phenotype of knockout mice are discouraged from submitting applications to this FOA. Instead, they should submit applications in response PA-17-155 (R01)<https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_pa-2Dfiles_PA-2D17-2D155.html&d=DwMFAg&c=ST5Jxgx_zZ9nYuPWkSm01Luus8kzn0TCuX9tmQgnWms&r=AP2rDwfXnLanmfgmid0oPg&m=U-SsUu0R7wOxR8dXF_1DLF-7eazb5uQbkZqbjMHh3rA&s=b9yWQP7i7KKQCiTFi4T-lJeNk-VYR0yg5vk-32ncfrY&e=> PA-17-157 (R21)<https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_pa-2Dfiles_PA-2D17-2D157.html&d=DwMFAg&c=ST5Jxgx_zZ9nYuPWkSm01Luus8kzn0TCuX9tmQgnWms&r=AP2rDwfXnLanmfgmid0oPg&m=U-SsUu0R7wOxR8dXF_1DLF-7eazb5uQbkZqbjMHh3rA&s=cQsfIRkmz09QPgpchcg2iz2kCbz-US3Lw9XHd-XLxUA&e=> Functional Genetics, Epigenetics, and Non-coding RNAs in Substance Use Disorders.”

This FOA will replace PAR-15-120<https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_pa-2Dfiles_par-2D15-2D120.html&d=DwMFAg&c=ST5Jxgx_zZ9nYuPWkSm01Luus8kzn0TCuX9tmQgnWms&r=AP2rDwfXnLanmfgmid0oPg&m=U-SsUu0R7wOxR8dXF_1DLF-7eazb5uQbkZqbjMHh3rA&s=G0yS_GF34nvMBvUvXD73Ow0vd-t1At6jYcR0DdqdXfo&e=> "Identification of Genetic and Genomic Variants by Next-Gen Sequencing in Non-human Animal Models (U01)."

The next application due date is March 19, 2019.  This is reviewed by a NIDA special emphasis panel.  This research area is of high programmatic interest to my branch.

If interested, please contact:

Amy C. Lossie, PhD
National Institute on Drug Abuse (NIDA)
Phone: 301-827-6092
lossieac@mail.nih.gov

Or me:

Jonathan D. Pollock, Ph.D., Chief
Genetics, Epigenetics, and Developmental Neuroscience Branch
Division of Neuroscience and Behavior
National Institute on Drug Abuse, NIH
6001 Executive Blvd, Rm. 4267
Bethesda, MD 20892
Tel. 301-435-1309
jpollock@mail.nih.gov

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