Translational Research Technologies

Together, the institutions of the Northern New England Clinical and Translational Research Network house state-of-the-art infrastructure, backed up with technical expertise that enable cutting edge research and data analysis for biomedical research. The Translational Research Technologies Core provides point-of-entry access to these resources at institutional rates for investigators registered with the network.

Genomics

Genomics and Molecular Phenotyping

Next-generation sequencing, qPCR, RNA-seq, SNP detection, single-cell genomics and transcriptomics, microarray analysis

microscopy

Imaging

High-resolution confocal microscopy, live-cell imaging, immunofluorescence microscopy, FRET, whole-slide imaging

 

Physiology_Seahorse data

Physiological Phenotyping

Metabolic monitoring, bioenergetic analysis, immunoassays, biochemical tolerance assessment, small-animal imaging

Tissue20161114_goller_03

Tissue Management and Processing

Retrieval and distribution of de-identified/coded banked specimens: fresh-frozen surgical resection specimens of tumor and (as possible) normal tissues, histopathology

proteomics

Proteomics and Lipidomics

 

Protein identification and quantitation by SWATH, proteome discovery with SEQUEST identification of post-translational modifications, lipid profiling