Featured Publications
Lee AJ, Majumdar C, Kathe SD, Van Ostrand RP, Vickery HR, Averill AM, Nelson SR, Manlove AH, McCord MA, David SS (2020) Detection of OG:A lesion mispairs by MutY relies on a single his residue and the 2-amino group of 8-oxoguanine. J Am Chem Soc, 142, 31, 13283-13287.
Nelson SR, Kathe SD, Hilzinger TS, Averill AM, Warshaw DM, Wallace SS, Lee AJ (2019) Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant. Nucleic Acids Res, 47(6), 3058-3071.
Nelson SR, Dunn AR, Kathe SD, Warshaw DM, & Wallace SS (2014) Two glycosylase families diffusively scan DNA using a wedge residue to probe for and identify oxidatively damaged bases. Proc Natl Acad Sci U S A 111(20):E2091-2099.
Lee AJ, Warshaw DM, & Wallace SS (2014) Insights into the glycosylase search for damage from single-molecule fluorescence microscopy. DNA Repair (Amst) 20:23-31.