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The practice of medicine is an art, not a trade, a calling, not a business, a calling in which your heart will be exercised equally with your head.
-Sir William Osler
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Dwight Matthews, PhD
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Professor of Medicine and Chemistry |
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Chairman, Department of Chemistry
The University of Vermont
Cook Physical Sci Bldg
office: Rm A205 lab: Rm A113
82 University Place
Burlington, VT 05405
tel: 802 656-8114
fax: 802 656-8705 |
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dwight.matthews@uvm.edu
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Academic Interests
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Mass spectrometry
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Stable isotope tracers
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Metabolism
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Amino acid metabolism
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Protein metabolism
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Energy metabolism
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Clinical Expertise
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Metabolism
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Education
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Ph.D. - Analytical Chemistry, Indiana University, Bloomington, Indiana, December 1977.
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B.A. - DePauw University, Greencastle, Indiana, May 1973.
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Professional Societies
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American Chemical Society (ACS)
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American Federation for Medical Research (AFMR)
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American Physiological Society (APS)
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American Society for Biochemistry and Molecular Biology (ASBMB)
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American Society for Clinical Nutrition ( ASCN)
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American Society for Mass Spectrometry (ASMS)
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American Society for Nutritional Sciences (ASNS)
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American Society for Parenteral and Enteral Nutrition (ASPEN)
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North American Association for the Study of Obesity (NAASO)
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Publications
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Selected Recent Publications:
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ME Jennings, II & DE Matthews: Determination of complex isotopomer patterns in isotopically labeled compounds by mass spectrometry. Anal. Chem., 77: 6435-6444, 2005.
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MJ MacCoss & DE Matthews: Quantitative mass spectrometry for proteomics: Teaching a new dog old tricks. Anal. Chem. 77: 294A-302A, 2005.
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DE Matthews: Observations of branched-chain amino acid administration in humans. J. Nutr. 135: 1580S-1584S, 2005.
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MJ Toth, DE Matthews, PA Ades, MD Tischler, P Van Buren, MJ Previs & MM LeWinter: Skeletal muscle myofibrillar protein metabolism in heart failure: relationship to immune activation and functional capacity. Am. J. Physiol. Endocrinol. Metab. 288: E685-E692, 2005.
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MJ Toth, DE Matthews, RP Tracy & MJ Previs: Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation. Am. J. Physiol. Endocrinol. Metab. 288: E883-E891, 2005.
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JA Henkin, ME Jennings, DE Matthews & JO Vigoreaux: Mass processing--an improved technique for protein identification with mass spectrometry data. J. Biomol. Tech. 15: 230-237, 2004.
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CC Wu, MJ MacCoss, KE Howell, DE Matthews &JR Yates, III: Metabolic labeling of mammalian organisms with stable isotopes for quantitative proteomic analysis. Anal. Chem. 76: 4951-4959, 2004.
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A Battezzati, A Caumo, F Martino, LP Sereni, J Coppa, R Romito, M Ammatuna, E Regalia, DE Matthews, V Mazzaferro &L Luzi: Nonhepatic glucose production in humans. Am. J. Physiol. Endocrinol. Metab. 286: E129-E135, 2004.
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M Rosenbaum, K Vandenborne, R Goldsmith, JA Simoneau, S Heymsfield, DR Joanise, J Hirsch, E Murphy, D Matthews, KR Segal & RL Leibel: Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285: R183-R192, 2003.
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R Persinger, Y Janssen-Heininger, SS Wing, DE Matthews, MM LeWinter & MJ Toth: Effect of heart failure on the regulation of skeletal muscle protein synthesis, breakdown, and apoptosis. Am. J. Physiol. Endocrinol. Metab. 284: E1001-E1008, 2003.
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Book Chapters
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Recent Book Chapters:DE Matthews: Techniques to assess in-vivo tissue metabolism directly in humans without biopsy samples. Curr. Opin. Clin. Nutr. Metab. Care 7: 513-514, 2004.
EJ Parks & DE Matthews: A.S.P.E.N. 2003 Research Workshop on using tracers to measure carbohydrate, fat, and amino acid metabolism in humans. JPEN J. Parenter. Enteral Nutr. 28: 38-53, 2004.
DE Matthews & JB van Goudoever: General concepts of protein metabolism. In: Fetal and Neonatal Physiology, RA Polin, WW Fox & SH Abmans, eds. Philadelphia: W.B. Saunders, 2004, 501-509.
DE Matthews: MRS and NMR: short abbreviations for powerful techniques, but what can they do for you? Curr. Opin. Clin. Nutr. Metab. Care 6: 497-498, 2003.
DE Matthews: MRS and NMR: short abbreviations for powerful techniques, but what can they do for you? Curr. Opin. Clin. Nutr. Metab. Care 6: 497-498, 2003.
DE Matthews: Evidence-based medicine: sifting through the literature to reach conclusions is not a simple task. Curr. Opin. Clin. Nutr. Metab. Care 5: 463-464, 2002.
DE Matthews: What is more exciting than 'genomics'? 'Proteomics'. Curr. Opin. Clin. Nutr. Metab. Care 4: 339, 2001.
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Search for more publications on Pub med
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