Sigmon Reports on Study of Waitlisted Opioid-Dependent Adults in New England Journal of Medicine, Results Make National Headlines
In rural states like Vermont, opioid-dependent adults desperate for treatment often find themselves stuck on a wait list, sometimes for eight months or more, increasing their risk of continuing to use illicit opioids, contract an infectious disease, overdose and prematurely die. However, this problem isn’t limited to Vermont – a full 96 percent of states in the U.S. have opioid dependence rates that exceed medication-assisted treatment availability. Stacey Sigmon, Ph.D., an addiction research expert with the VCBH and an associate professor in psychiatry at the University of Vermont, has seen the problem firsthand as the director of the Chittenden Clinic Opioid Treatment Program based in Burlington. Vermont’s largest methadone clinic, the Chittenden Clinic recently increased capacity from 400 to 1,000 patients, but waitlists for treatment persist.
Sigmon conducted a study to test an “Interim Buprenorphine Treatment” (IBT) regimen for waitlisted opioid-dependent adults. The results debut in the New England Journal of Medicine on December 22, 2016. In her National Institute on Drug Abuse-funded study, participants were randomized to receive IBT or continued “Waitlist Control” for three months. IBT participants received buprenorphine maintenance dispensed via a small computerized device, daily monitoring calls via an Interactive Voice Response (IVR) phone system, and IVR-generated random call-backs. IBT participants made bi-weekly clinic visits for assessment, at which time urine specimens were collected under staff observation and analyzed immediately for opioids and other drugs. Not only did IBT participants achieve far more illicit opioid abstinence, they also demonstrated greater reductions in their frequency of injection drug use and also in psychological symptoms, such as anxiety and depression.
Read coverage of IBT by the Associated Press.